zalcitabine


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  • noun

Synonyms for zalcitabine

an antiviral drug used to combat HIV infection

References in periodicals archive ?
For instance, both zalcitabine and didanosine may cause tingling or pain in the hands, feet and legs, so they shouldn't be prescribed together.
Several factors raised chances that cardiotnyopathy would develop (Figure 2): older age when triple therapy began, being a boy, being Hispanic, using Hivid (zalcitabine) before triple therapy, and using Retrovir (zidovudine) in a first triple combination with a lowest-ever CD4 percent below 15%.
Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells.
Zidovudine, didanosine, zalcitabine, stavudine, and lamivudine all got the FDA green light before clinicians could craft a regimen with drugs from two classes.
Then in 2001, lamivudine (3TC), stavudine (D4T), zalcitabine (DDC), didanosine (DDI), and indinavir (IDV) were produced.
Potency estimations in vitro gave a descending hierarchy of their potency: zalcitabine, didanosine, stavudine, zidovudine and, finally, abacavir, as least toxic [28].
Kim and Chien (15,16) studied the effect of NMP on the skin permeation of the anti-HIV drugs zalcitabine, didanosine, and zidovudine using hairless rat skin at 37[degrees]C.
Table 1 Common Antiretroviral Drugs (14-16) Classification Generic Name Trade Name Nucleoside reverse Abacavir sulfate Ziagen transcriptase inhibitors Abacavir sulfate + Trizivir (NRTI) lamivudine + zidovudine Didanosine (ddl) Videx, Videx EC Lamivudine (3TC) Epivir Lamiudine + zidovudine Combivir Stavudine (d4T) Zerit Tenofovir disoproxil Viread fumarate Zalcitabine (ddC) Hivid Zidovudine (AZT, ZDV) Retrovir Non-nucleoside reverse Delavirdine mesylate Rescriptor transcriptase inhibitors Efavirenz Sustiva (NNRTI) Nevirapine Viramune Protease inhibitors (PI) Amprenavir Agenerase Indinavir sulfate Crixivan Lopinavir + ritonavir Kaletra Nelfinavir Viracept Ritonavir Norvir Saquinavir Fortovase Saquinavir mesylate Invirase Fusion inhibitors (FI) Enfuvirtide Fuzeon
Which of the following viral proteins is the primary target for the cytidine analogues--lamivudine, zalcitabine, and emtricitabine?
This category includes zidovudine (ZDV), didanosine (ddI), stavudine (d4T), lamivudine (3TC), zalcitabine (ddC), and abacivir (ABC).
(74.) The three drugs are didanosine (ddI), zalcitabine (D4T) and idovudine (AZT).
To explore the relationship between a classic assay for mitochondrial function (lactate/pyruvate ratio) and the real-time duplex NASBA method, we cultured control human fibroblasts (purchased from the Corriell Cell Repository, Camden, NJ) in DMEM supplemented with 100 mL/L FCS and antibiotics in the presence of the antiretroviral drug zalcitabine (ddC; 30 [micro]mol/L) for 4 weeks.
Currently, three groups of drugs are available for the treatment of the HIV infection: the nucleoside inhibitors of reverse transcriptase (zidovudine, didanosine, lamivudine, stavudine, abacavir, zalcitabine), the non-nucleoside inhibitors of reverse transcriptase (nevirapine, delavirdine, efavirenz), and the protease inhibitors (indinavir, nelfinavir, ritonavir, saquinavir, amprenavir, lopinavir).
The five nucleoside analogs available during the study period were: zidovudine (azt), didanosine (ddi), zalcitabine (ddc), stavudine (d4t), and lamivudine (3tc).
Data from transcripts were coded, first, for use of medication--whether people reported taking any antiretroviral medication (such as AZT, didanosine [ddI], or zalcitabine [ddc]), protease inhibitors, or preventive medication for opportunistic infections such as PCP.