zalcitabine


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  • noun

Synonyms for zalcitabine

an antiviral drug used to combat HIV infection

References in periodicals archive ?
Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells.
It dates back at least to the dawn of HAART, when German researchers offered results on nanoparticle porters of saquinavir and zalcitabine.
Potency estimations in vitro gave a descending hierarchy of their potency: zalcitabine, didanosine, stavudine, zidovudine and, finally, abacavir, as least toxic [28].
Kim and Chien (15,16) studied the effect of NMP on the skin permeation of the anti-HIV drugs zalcitabine, didanosine, and zidovudine using hairless rat skin at 37[degrees]C.
Table 1 Common Antiretroviral Drugs (14-16) Classification Generic Name Trade Name Nucleoside reverse Abacavir sulfate Ziagen transcriptase inhibitors Abacavir sulfate + Trizivir (NRTI) lamivudine + zidovudine Didanosine (ddl) Videx, Videx EC Lamivudine (3TC) Epivir Lamiudine + zidovudine Combivir Stavudine (d4T) Zerit Tenofovir disoproxil Viread fumarate Zalcitabine (ddC) Hivid Zidovudine (AZT, ZDV) Retrovir Non-nucleoside reverse Delavirdine mesylate Rescriptor transcriptase inhibitors Efavirenz Sustiva (NNRTI) Nevirapine Viramune Protease inhibitors (PI) Amprenavir Agenerase Indinavir sulfate Crixivan Lopinavir + ritonavir Kaletra Nelfinavir Viracept Ritonavir Norvir Saquinavir Fortovase Saquinavir mesylate Invirase Fusion inhibitors (FI) Enfuvirtide Fuzeon
Which of the following viral proteins is the primary target for the cytidine analogues--lamivudine, zalcitabine, and emtricitabine?
This category includes zidovudine (ZDV), didanosine (ddI), stavudine (d4T), lamivudine (3TC), zalcitabine (ddC), and abacivir (ABC).
The three drugs are didanosine (ddI), zalcitabine (D4T) and idovudine (AZT).
To explore the relationship between a classic assay for mitochondrial function (lactate/pyruvate ratio) and the real-time duplex NASBA method, we cultured control human fibroblasts (purchased from the Corriell Cell Repository, Camden, NJ) in DMEM supplemented with 100 mL/L FCS and antibiotics in the presence of the antiretroviral drug zalcitabine (ddC; 30 [micro]mol/L) for 4 weeks.
The five nucleoside analogs available during the study period were: zidovudine (azt), didanosine (ddi), zalcitabine (ddc), stavudine (d4t), and lamivudine (3tc).
Data from transcripts were coded, first, for use of medication--whether people reported taking any antiretroviral medication (such as AZT, didanosine [ddI], or zalcitabine [ddc]), protease inhibitors, or preventive medication for opportunistic infections such as PCP.
Zalcitabine, didanosine and abacavir can also select for this mutation.
The agents in this class include: zidovudine (Retrovir[R]), didanosine (Videx[R]), zalcitabine (Hivid[R]), stavudine (Zerit[R]), lamivudine (Epivir[R]), lamivudine/ zidovudine (Combivir[R]), and the newest NRTI, abacavir (Ziagen[R]).
These expensive drugs include Ziovudine (AZT), Zalcitabine (ddc), Didanosine (ddi), Stavudine (d4t), Nevirapine, Lamivudine 3TC, Saquinavir Mesylate, Indinavir Sulphate, and Ritonavir (Fishel et al, 1996).