References in periodicals archive ?
Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells.
It dates back at least to the dawn of HAART, when German researchers offered results on nanoparticle porters of saquinavir and zalcitabine.
Category I consists of Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs) items, namely abacavir, didanosine, lamivudine, stavudine, zalcitabine and zidovudine.
For instance, both zalcitabine and didanosine may cause tingling or pain in the hands, feet and legs, so they shouldn't be prescribed together.
To explore the relationship between a classic assay for mitochondrial function (lactate/pyruvate ratio) and the real-time duplex NASBA method, we cultured control human fibroblasts (purchased from the Corriell Cell Repository, Camden, NJ) in DMEM supplemented with 100 mL/L FCS and antibiotics in the presence of the antiretroviral drug zalcitabine (ddC; 30 [micro]mol/L) for 4 weeks.
The five nucleoside analogs available during the study period were: zidovudine (azt), didanosine (ddi), zalcitabine (ddc), stavudine (d4t), and lamivudine (3tc).
Data from transcripts were coded, first, for use of medication--whether people reported taking any antiretroviral medication (such as AZT, didanosine [ddI], or zalcitabine [ddc]), protease inhibitors, or preventive medication for opportunistic infections such as PCP.
Zalcitabine, didanosine and abacavir can also select for this mutation.
The patient's medications on admission included zalcitabine, lamivudine, saquinavir, trimethoprim/ sulfamethoxazole, clindamycin, ciprofloxacin, ganciclovir, senna, naproxen, beclomethasone dipropionate, oxymetazoline HCl, morphine, potassium chloride, warfarin, and zolpidem.
Zalcitabine (ddC, Dideoxycytidine, HIVID), Hoffmann-La Roche
Antiretroviral utilization was defined as self-reported use of zidovudine, didanosine, or zalcitabine.
Treatment of Human Inmmunodeficiency Virus Infection with Saquinavir, Zidovudine, and Zalcitabine.
Zidovudine Alone or in Combination with Didanosine or Zalcitabine in HIV-infected Patients with the Acquired Immunodeficiency Syndrome or Fewer than 200 CD4 Cells Per Cubic Millimeter, 335 New Eng.
However, since tests of zalcitabine are still in progress, the FDA approved the drug's use only in combination with the AIDS drug zidovudine, or AZT.
Additive to synergistic antiretroviral activity was observed when human T-lymphoid cells infected with the H9IIIB variant of HIV-1 were incubated with raltegravir in combination with non-nucleoside reverse transcriptase inhibitors (delavirdine, efavirenz, or nevirapine); nucleoside analog reverse transcriptase inhibitors (abacavir, didanosine, lamivudine, stavudine, tenofovir, zalcitabine, or zidovudine); protease inhibitors (amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir, or saquinavir); or the entry inhibitor enfuvirtide.