(A) The model group with microvilli sloughing and mitochondria stretching, marked with 1 and 2 respectively; (B) Blank group with normal goblet cells and intestinal villi
, marked with 3 and 4 respectively; (C) Positive drug group with microvilli shortening and membrane of goblet cells damaged, marked with 5 and 6 respectively; D and E were for CK group and TP group with integral microvilli, marked with 7 and 8, normal cell-cell junction and nuclear membrane, marked with 9 and 10, respectively.
In some cases of abruptio placenta fibrinoid necrosis occurs, which are small collection of structureless, eosinophilic, homogeneous material within the villi
, usually 3% at term normally but increase in abruptio placenta.
Another frequent finding is fibrotic, avascular villi
with hemosiderin deposition.
In the two-dimensional approach of conventional histopathology, the small intestinal mucosal architecture is characterized by villi
and crypts lying side-by-side on the vertical plane, thereby justifying the concept of villus/crypt ratios for practicing pathologists.
Like our gut flora, intestinal villi
(and microvilli) are critical
Structurally the placenta is composed of chorionic villi
, which present typical features in a pregnancy in its physiological evolution.
On microscopy, sections from the placenta revealed [greater than or equal to]10 capillaries each in [greater than or equal to]10 terminal villi
in [greater than or equal to]10 non-infarcted areas examined in [greater than or equal to]3 low power (10x) fields of placenta (Figures 1b, c).
The concentration of the simvastatin in the blood samples is directly related to the villous health of the patient; in patients with healthy villi
a high rate of metabolism leads to reduced concentration of simvastin in the blood samples whereas in patients with damaged villi
, the converse is true.
At 9 weeks, plenty of villi
were seen projecting into the lumen of the small intestine.
The mucosa consisted of 3 layers, including the epithelium, lamina propria, and muscularis mucosae, and is organized into villi
. In the duodenum, villi
were finger-like projections with pointed clear ends protruded into the intestinal lumen and lined by a single layer of columnar epithelium with basal oval nuclei and few goblet cells.
The chorionic villi
were large and cellular, with convoluted outlines and presence of both trophoblastic pseudoinclusions (Figure 2(c)), secondary to villous scalloping, and focal robust ferrugination of the basal lamina (Figure 2(c)), highlighted by iron stain (Figure 2(d)).
For a person who does not have tolerance for gluten, consuming wheat or any food product with gluten in them will cause their immune system to affect the villi
that line the inner wall of the small intestine.
Aging in intestinal stem cells leads to changes in villi
, the finger-shaped protuberances that line the small intestine and absorb nutrients, and crypts, the valleys between villi
where the intestinal stem cells live.
In the small intestines, the mucosa and the submucosa are folded to form the villi
. The lamina propria as a loose connective tissue is largely occupied by tubular intestinal glands.
Significant difference was observed among treatments in different parts of the intestine including villi
width, crypt depth, and thickness of the epithelium (p < 0.05).