uveoscleral pathway


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Related to uveoscleral pathway: pilocarpine, uveoscleral drainage
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  • noun

Words related to uveoscleral pathway

a tubule that drains excess aqueous humor

References in periodicals archive ?
If approved, Roclatan would be the first glaucoma product to lower IOP by increasing fluid outflow through the trabecular meshwork, the eye's primary drain, increasing fluid outflow through the uveoscleral pathway, the eye's secondary drain, reducing fluid production in the eye and reducing episcleral venous pressure (EVP).
In the past it was believed that this 'unconventional' uveoscleral pathway accounted for only 10% of aqueous outflow from the eye, with 90% leaving via the trabecular meshwork.
In the ageing eye, there is increased resistance to aqueous outflow via both the trabecular pathway and uveoscleral pathway. This may be as a result of an increase in trabecular beam thickness (and possibly stiffness) and an increase in extracellular material within the supraciliary space in the aged eye.
in some individuals, aqueous outflow may be evenly distributed between the trabecular meshwork and the uveoscleral pathway
Based on the company's preclinical studies and clinical trials to date, Aerie believes that Roclatan, if approved, would be the first glaucoma product to lower IOP through all known mechanisms, including increasing fluid outflow through the trabecular meshwork, the eye's primary drain, increasing fluid outflow through the uveoscleral pathway, the eye's secondary drain, reducing fluid production in the eye, and reducing episcleral venous pressure.