A new global guideline on chronic urticaria
(UC) has recommended Novartis' (VTX: NOVN) Xolair (omalizumab) as an add-on therapy for the treatment of chronic spontaneous urticaria
(CSU) for patients who are not responding to antihistamines, the company disclosed on Tuesday.
is the medical term for hives, a skin rash reaction that occurs due to exposure to an irritant.
is rare and fewer than 100 occurrences have been recorded in medical literature since the first cases were described in 1964.
He presented year-1 results from 1,550 participants at 256 sites across Germany participating in the AWARE study (A Worldwide Antihistamine-Refractory Chronic Urticaria
Comment: Some 75-95% of cases of chronic urticaria
(defined as lasting longer than 6 weeks) are considered by most physicians to be idiopathic.
Patients of chronic autoimmune urticaria
were prospectively analyzed for the efficacy of eight consecutive weekly autologous serum injections with a post-intervention follow-up of 12 weeks.
Angioedema has been previously reported in four patients treated with oral retinoids: isotretinoin (two cases without urticaria
and two cases with associated urticaria
) and in two patients treated with oral acitretin (one case with and one case without urticaria
is a serious disease that greatly impacts the quality of life, yet seems to be severely undertreated," said Vas Narasimhan, Global Head, Drug Development and Chief Medical Officer, Novartis.
Material and Methods: The medical data of children who were diagnosed as having urticaria
admitted to our outpatient clinic between January 2014 and January 2016 were searched.
Dr North said: "It can be difficult to tell an allergic rash or swelling from one that occurs due to overactivity of the immune system as with spontaneous urticaria
NASDAQ: CXRX) (TSX: CXR) has closed the acquisition of the global rights to four generic products, for the treatment of anemia, depression and urticaria
, the company said.
Global Markets Direct's, 'Chronic Urticaria
Or Hives - Pipeline Review, H1 2016', provides an overview of the Chronic Urticaria
Or Hives pipeline landscape.
is defined as a skin lesion consisting of a wheal-andflare reaction in which localized intracutaneous oedema (Wheal) is surrounded by an area of redness (Erythema) that is typically pruritic.
Although not the most classic presentation, this patient's migrating rash is most consistent with urticaria
(from the case described on p.
(CU) is defined as urticaria
that has been continuously or intermittently present for at least six weeks .