M2 EQUITYBITES-March 6, 2018-New global chronic urticaria
guideline recommends Novartis' Xolair
is the medical term for hives, a skin rash reaction that occurs due to exposure to an irritant.
A 47-year-old Hispanic male was initially referred to the Mayo Clinic at 34 years of age due to severe episodes of angioedema (occurring every three to four months) and history of chronic urticaria
. The initial onset of urticaria
occurred in 2002 while the proband was living in Italy.
In a previous study, we observed that the prevalence of inducible urticaria
self-reported was 75%, but the prevalence based on positive challenge tests was only 36%, indicating that a high number of patients did unnecessary restrictions .
It has been estimated that one in every 100-200 European adults has been diagnosed with chronic urticaria
, with CSU and females accounting for about two-thirds of the cases [4, 5].
During the course of my research I found surprising causes of urticaria
. For instance, there's a type that exercise can bring on, called cholinergic urticaria
The red lumps can be round, 1cm in diameter, or can be large patches with irregular borders, a type called geographic urticaria
In January 2019, Aralez partnered with the Canadian Asthma, Allergy and Immunology Foundation (CAAIF) to provide an unrestricted research grant of $50,000 for Canadian research focused on the study of allergic rhinitis and/or urticaria
. The CAAIF is a charitable organization that was established to increase educational opportunities and research resources for the Canadian Allergy, Asthma and Immunology community.
The overall standardized prevalence of chronic urticaria
in the United States at 0.23%, or 229.8 per 100,000 adults, reported Sara Wertenteil, BA, and her associates at Hofstra University, Hempstead, N.Y.
is marked by itchy wheals that vary in flare-type dermal reactions, distribution, number and size.1 Urticaria
can be an acute (less than 6 weeks) or a chronic urticaria
(more than 6 weeks).2 Chronic urticaria
(CU) is either idiopathic chronic (55%) and autoimmune chronic (45%) without urticarial vasculitis and physical urticaria
Clinical features and natural history of physical urticaria
Mast cell mediators are usually associated with urticaria
and itch, whereas bradykinin has no association.
In very lengthy Instagram posts, Kris shared that her doctor in Singapore diagnosed her with Chronic Spontaneous Urticaria
(CSU), "a serious, chronic and distressing skin condition that is difficult to diagnose and manage," according to Novartis.co.uk data.
Hamad Medical Corporation's (HMC) Allergy and Immunology Service has been accredited as an Urticaria
Center of Reference and Excellence by the Global Allergy and Asthma European Network (GAALEN).
Tribune News Network Doha HAMAD Medical Corporation's (HMC) Allergy and Immunology Service has been accredited as an Urticaria
Center of Reference and Excellence by the Global Allergy and Asthma European Network (GA'b2LEN).