The [5-HT.sub.1A] agonist 8-OH-DPAT administered to rats with spinal cord injury increased the external urethral sphincter
relaxation period (11).
Stem-cell Injections for Urethral Sphincter
Very little is known about the behavior of bladder under different circumstances especially if we consider the effect of gender and BMI.1,4,8,9 As mentioned in Guyton text book of medical physiology the higher centers have inhibitory control over external urethral sphincter
by pudendal nerve.
(12) Surgical options for treatment of UI include retropubic suspension, slings, and, in some instances, artificial urethral sphincters
(15) In brief, the urethral sphincter
system and periurethral support system are two main mechanisms of preserving urinary continence.
Male patients with moderate to severe stress urinary incontinence after orthotopic ileal neobladder surgery might be considered for artificial urethral sphincter
(AUS) implantation.[sup],,, The overall postoperative continence rate of this procedure is 70-95%.
In a four-year review of cases presenting to their centre, Kavia and colleagues reported Fowlers syndrome (poor relaxation of the external urethral sphincter
) as the most common cause of female urinary retention.
The effect of vaginal delivery on the urethral sphincter
. British Journal of Obstetrics and Gynaecology 95, 142-146.
Chae et al., "Combined injection of three different lineages of early-differentiating human amniotic fluid-derived cells restores urethral sphincter
function in urinary incontinence," BJU International, vol.
M Muazhar Hussain of Army Medical College, Rawalpindi said that requirements of for urinary continence include a quiescent bladder, functioning musculofascial supports and a functional urethral sphincter
Pelvic floor exercises entail repetitive voluntary contraction and relaxation of the urethral sphincter
, performed multiple times per day for a course of at least a few months initially.
In such cases I squeeze my urethral sphincter
, and it aches all the way up into my enfolding organs.
(9), (10) Electromyography (EMG) revealed abnormal bursts of activity of the striated urethral sphincter
, resulting in a functional obstruction, the so-called Fowler's syndrome.
Detrusor sphincter dysynergia (DSD) is a consequence of a neurological pathology such as spinal injury (Karsenty, 2005) or multiple sclerosis (Stankovich et al., 1999) that disrupts central nervous system regulation of the micturition reflex resulting in dyscoordination of the detrusor muscles of the bladder and the external urethral sphincter