urate

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  • noun

Words related to urate

a salt of uric acid

References in periodicals archive ?
The saturated fat in full-fat dairy helps to prevent urates from being lost from the body.
Gout or acute inflammatory arthritis is primarily due to raised blood urate levels within the bloodstream (Lorimer, D.
* Monosodium urate monohydrate microcrystals in joint fluid during attack
Synovial macrophages may be the first cells to recognize urate crystals in situ and to initiate the inflammation of a gouty attack.
Mitroulis and colleagues bring these two threads together with their discovery that monosodium urate crystals can lead to the activation to neutrophil extracellular traps, or NETS.
They also analyzed the prevalence of hyperuricemia and the serum urate levels.
Analysis revealed that the cloacolith was composed of 100% salts of uric acid (urates).
Treatment in all stages of gout should be tailored to specific risk factors (serum urate level, radiographic evidence), clinical phase (acute, intercritical, or chronic), and general risk factors (gender, age, obesity, alcohol use, urate elevating drugs, and other comorbidities), according to the guidelines.
Massive amounts of amorphous urates can obscure clinically significant formed elements in urine on microscopic examination.
(6) Each participant consumed 80 grams of casein, lactalbumin, or soy protein, followed by measurement of serum and urinary urate levels for the next 180 minutes.
Cytologic examination of the white to yellow chalky aspirate material showed monosodium urate crystals (arrow, Fig 3), which were birefringent under polarized light (arrow, Fig 4).
In 1679, Anton von Leeuwenhoek, the inventor of the microscope, first saw urate crystals, but it would be several hundred years before the great English physician Alfred Garrod affirmed that urate was "the cause of gouty inflammation." In 1931, Garrod's son Archibald, author of the first clinical genetics textbook, declared gout an "inborn error of metabolism." By 1961, McCarty and Hollander had initiated the use of the polarizing microscope, helpful in the study of crystals.
It inhibits the main renal urate transporter, URAT-1, an exchanger located in the luminal face of the proximal tubule of the kidney.
Now we address the remaining stones that can affect our best friends: urate, cystine, calcium phosphate, silica, xanthine, and mixed or compound uroliths.
A Boots Herbalist Sue Jamieson says: Gout is caused by a deposit of urate crystals in tissues or joints leading to an acute inflammatory response.