oxidase

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Related to urate oxidase: uricase, allopurinol
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  • noun

Words related to oxidase

any of the enzymes that catalyze biological oxidation

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References in periodicals archive ?
Rasburicase is a recombinant urate oxidase that converts uric acid to the highly soluble form allantoin.
recombinant urate oxidase (rasburicase) in the prevention and treatment of malignancy-associated hyperuricemia in pediatric and adult patients: results of a compassionate-use trial.
One such drug currently under investigation is the pegylated form of urate oxidase, a compound that dissolves urate and that traditionally has been used in leukemia patients who have massive loads of urate, he said.
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene) glycol (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase. Arthritis Res Ther.
The poster presentation includes data demonstrating urate reduction in a urate oxidase knock-out mouse model, an animal model of severe hyperuricemia with kidney damage due to urate crystal deposition.
Rasburicase is a recombinant urate oxidase that is used primarily for the prevention and treatment of acute HUA in patients with hematological malignancies, especially HUA caused by radiochemotherapy.
Takahata, "Loss of urate oxidase activity in hominoids and its evolutionary implications," Molecular Biology and Evolution, vol.
It is a pure recombinant form of urate oxidase, an enzyme responsible for the breakdown of UA into allantoin, which is easily soluble and readily removed [58].
Caskey, "Two independent mutational events in the loss of urate oxidase during hominoid evolution," Journal of Molecular Evolution, vol.