Indeed 5-bromo uracil
possesses the capability to replace a normal nucleobase in nucleic acids.
Caption: Figure 2: HPTLC chromatogram (a), 3D spectra (b), and quantities (c) of nucleobases identified in aqueous extracts and PRFs of Ganoderma lucidum mycelium and fruiting body (T: thymine; U: uracil
; Ad: adenine; C: cytosine; Gs: guanosine).
The concentrations of the components in the mixed solution were as follows: uracil
33.8 [micro]g/mL, uridine 93.6 [micro]g/mL, adenine 30.1 [micro]g/mL, guanosine 120.8 [micro]g/mL, and adenosine 93.6 [micro]g/mL.
At the active site formed by chains A and B, uracil
is sandwiched in [pi]-stacking interactions with [F43.sub.B] and [Y49.sub.B] (F41 and Y47 in E.
Deamination of cytosine and 5-mC results in uracil
and thymine bases, creating U:G and T:G mismatches, respectively.
In the biosynthetic pathway of pyrimidine nucleosides, ribose and uracil
are the two products catalyzed by uridine nucleosidase.
Component B was a solution of 0.001 mol/L uracil
in TRIS buffer.
The results of the present study demonstrated a significant increase in uracil
content in EC tissues, which further confirmed that glutaminolysis was an indispensable metabolic pathway of de novo synthesis of purine and pyrimidine bases.
For growth of the uracil-auxotrophic strain, 0.02 g/L uracil
was added to XT medium (XTU).
Adenine and uracil
are stimulatory nucleic acids which had an effect on the growth of E.
All isolates belonging to the new EV-A71 CI variant carried uracil
at this position.
An analytical method has been proposed for the separation and determination of guanine, adenine, cytosine, thymine and uracil
by gas chromatography (GC) following precolumn derivatization using ethyl chloroformate.
Last year, researchers created uracil
, cytosine and thymine--three of the molecular letters in DNA's and RNA's genetic alphabets--in a simulated space environment.
The supply of [beta]-alanine is dependent both on the hepatic synthesis from uracil
and on the diet .
In view of a pronounced effect of Microwave-assisted methods in synthetic chemistry and their importance in drug discovery, a systematic work on the solvent-free synthesis of 2,4-(IH,3H)Pyrimidinedione(uracil
) was carried out.