After stabilization (20min), tubocurarine
or individual alkaloids were added cumulatively in order to establish concentration-inhibition curves.
Blood products, iodine contrast, opioids and even tubocurarine
are commonly associated with anaphylactoid reactions.
However, charged molecules such as tubocurarine
can also enter the fetus (Kivalo and Saarikoski 1972, 1976).
However, some neuromuscular blockers such as tubocurarine
may cause direct release of histamine.
A number of modern drugs like aspirin, atropine, ephedrine, digoxin, morphine, quinine, reserpine and tubocurarine
are examples, which were originally discovered through observations of traditional cure methods of indigenous peoples [Gilani and Rahman, 2005].
In 1950, after a decade of 11 other unpublished New Zealand cases of tetanus with two recoveries, and another series treated by basal sedation with 50% surviving, DW Beaven (50) and his Christchurch team supplied a six-year-old boy with anaesthetic doses of tribromoethanol with 350 mg tubocurarine
(d-TC) over [greater than or equal to] 12 days, to control his tetanus spasms and severe opisthotonus.
To name only a few of the important drugs in use today, aspirin, atropine, ephedrine, digoxin, morphine, quinine, reserpine and tubocurarine
serve as examples (Gilani, A.