in primary insomnia: results of a polysomnographic double-blind controlled study.
Some success was reported with the tricyclic antidepressants amitriptyline (4) and nortriptyline, (5,6) but Mihail et al (7) found that trimipramine
was not superior to placebo.
The non-SSRIs used were amitriptyline, clomipramine, imipramine, lofepramine, nortriptyline, maprotiline, mianserin, moclobemide, trimipramine
, and venlaflaxine.
My next anti- depressant treatment was trimipramine
(Surmontil at 14p a pill) which was prescribed by a psychiatrist.
Salt-joining makes a hydrophobic molecule hydrophilic; the result, especially in psychoactive drugs, is improved kinetics, absorption, or physicochemical properties (eg, stability, hygroscopicity, fluidity)Y This may be the reason for differences identified between generic and brand-name amitriptyline, nortriptyline, desipramine, and trimipramine
Hypotensive cardio-circulatory failure and metabolic acidosis after suicidal intoxication with trimipramine
Some of the most frequently prescribed tricyclics are amitriptyline (Elavil, Endep), desipramine (Norpramin), clomipramine (Anafranil), doxepin (Sinequan), imipramine, (Tofranil, Tofranil PM), nortriptyline (Pamelor, Aventyl), amoxapine (Asendin), protriptyline (Vivactil) and trimipramine
In preselected populations designed to detect CYP2D6-related pharmacokinetic differences (33, 34), trimipramine
and doxepin clearance differed significantly between carriers of two or only one functional allele.
Bupropion, mirtazapine, nefazodone, trazodone, desipramine, nortriptyline, trimipramine
Selected psychotropics that affect P-glycoprotein Substrates Amitriptyline Paroxetine Carbamazepine Quetiapine Chlorpromazine Risperidone Citalopram Sertraline Doxepin Topiramate Nortriptyline Venlafaxine Olanzapine Inhibitors Amitriptyline Imipramine Carbamazepine Nefazodone Chforpromazine Paroxetine Desipramine Sertraline Disulfiram Thioridazine Fluoxetine Trifluoperazine Fluvoxamine Trimipramine
Haloperidol Inducers(a) Amitriptyline Phenothiazines Nefazodone Trazodone (a.
TCAs studied included amitriptyline, imipramine, clomipramine, doxepin, dothiepin, trimipramine
, and lofepramine.