When it is established that hyperkalaemia is secondary to trimethoprim
, the offending drug (and others that might exacerbate the situation) must be discontinued with immediate effect.
By combining Trimethoprim
; a diaminopyrimidine, enhances the killing ability of pathogens by TMP-SMX.
The aim of this study was to develop and validate a rapid, simple (without the need of solid-phase extraction (SPE) cartridges or similar materials), and reliable multiresidue method for the identification and quantification of sulfonamides and trimethoprim
in tilapia fillets (Oreochromis niloticus) by LC-QTOF/MS, to be suitable for application in monitoring programmes as well as in pharmacokinetic and residue depletion studies.
According to previous reports on the comportment of LAB towards antibiotics, Lactococcus strains are resistant to Trimethoprim
 and rifampicin.
coli that was sensitive to other antibiotics, the rate of resistance transfer was between 69% and 83% for tetracycline, trimethoprim
, and streptomycin.
Comorbidity of mothers was assessed through the National Hospital Register on the basis of diagnoses made between 1995 and 2005.This was done to assess whether women treated with trimethoprim
were more likely to be diagnosed with a teratogenic infection or conditions potentially harmful to the fetus.
An increased use of trimethoprim
could jeopardise that option, Dr Howe has warned.
casei DHFR as MTX under our assay conditions; trimethoprim
was 2.0% [+ or -] 0.6% as effective, and 7-OH-MTX was 1.7% [+ or -] 0.3% as effective as MTX (Fig.
Simultaneously, the use of other antimicrobials decreased: use of sulphonamides and trimethoprim
from 17.11 DDD/bed to 5.54 DDD/bed, amoxicillin from 6.56 DDD/bed to 2.18 DDD/bed, and the use of tetracycline varied during the study period from 0 DDD/bed to 7.64 DDD/bed.
"The establishment of basic manufacturing plant to produce Trimethoprim
, a vital ingredient used in production of antibiotic preparations under the brand name of Septran, is yet another milestone added to a long list of achievements in which the Wellcome Group and Pakistan Company can take some legitimate pride".
Typhi were cat for chloramphenicol, tetA for tetracycline, bla for ampicillin, strA-strB for streptomycin, and dfrA and sul1 for trimethoprim
and sulfonamide .
Within 112 days of their first or second febrile or symptomatic urinary tract infection (UTI), 302 young children diagnosed with vesicoureteral reflux (VUR) by voiding cystourethrogram were randomized to 3 mg of trimethoprim
plus 15 mg of sulfamethoxazole per kilogram; and 305 other VUR children were randomized to placebo.
If patient remains febrile past 5 days of treatment: trimethoprim/sulfamethoxazole 4-20 mg/kg/24 hours (dose based on trimethoprim
component) in equally divided doses every 12 hours (maximum: 320 mg trimethoprim
per 24 hours)"
Prescriptions for the first-line urinary anti-infective drugs trimethoprim/sulfamethoxazole, trimethoprim
, fosfomycin, and nitrofurantoin remained constant (P = .10).
diphtheriae biovar mitis, FRC24, expressed the following anti-microbial drug susceptibility profile: susceptible to penicillin, amoxicillin, ciprofloxacin, clindamycin, erythromycin, gentamicin, imipenem, kanamycin, rifampin, tetracycline, and vancomycin and resistant at an uncommonly high level to trimethoprim
, sulfamethoxazole, and co-trimoxazole with Etest (bioMerieux, Marcy l'Etoile, France) MICs of >32, >1,024, and >32 mg/L, respectively.