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While CNS stimulant drugs are prescribed to control the EDS associated with narcolepsy, tricyclic antidepressant drugs are prescribed to control cataplexy, sleep paralysis and hypnagogic hallucinations.
While no more effective than traditional tricyclic antidepressant drugs, the new agents are generally safer than traditional medications used to treat depression: they are well tolerated and, in case of overdose, less harmful than tricyclic antidepressants.