Brady, "ECG abnormalities in tricyclic antidepressant
ingestion," American Journal of Emergency Medicine, vol.
Predicting severity of tricyclic antidepressant
Treatment of amitriptyline poisoning with ovine antibody to tricyclic antidepressants
. Lancet 1999; 354: 1614-5.
A statistically significant association was found between respondents taking or not taking tricyclic antidepressant
therapy and cataplexy symptom ratings ([chi square] = 10.253, df = 3, p = 0.0165), as well as the remaining REM-sleep symptom ratings (hypnagogic hallucinations: [chi square] = 8.814, df = 3, p = 0.0319; sleep onset paralysis: [chi square] = 13.301, df = 3, p = 0.0040; awakening paralysis: [chi square] = 9.214, df = 3, p = 0.0266).
block the reuptake of serotonin and norepinephrine, are competitive inhibitors of [H.sub.1] and [H.sub.2] histamine receptors, have anticholinergic effects, and have quinidinelike effects on cell membranes.
Major Finding: Compared directly with tricyclic antidepressants
, SSRIs were associated with significantly higher rates of all-cause death (adjusted hazard ratio, 1.32), stroke or transient ischemic attack (HR, 1.15), falls (HR, 1.27), fractures (HR, 1.26), epilepsy or seizures (HR, 1.80), and hyponatremia (HR, 1.44).
We encountered a case of refractory hypotension following epidural administration of local anaesthetic during general anaesthesia in a patient who had been on long-term tricyclic antidepressant
therapy continued until the day before surgery.
A/ TRICYCLIC ANTIDEPRESSANTS
, duloxetine, pregabalin, oxycodone, and tramadol are all effective for the symptomatic treatment of painful diabetic neuropathy (strength of recommendation [SOR]: A, systematic reviews of randomized controlled trials [RCTs] and single RCTs).
Common prescription medications that cause constipation in this patient population include opioid, anticholingeric or tricyclic antidepressant
(26,29,31-35) For example, a tricyclic antidepressant
would be a good choice for a patient who is also de pressed but should be avoided if the patient has heart disease.
Warnings related to the risk of sudden death and cardiac dysrhythmias associated with desipramine have been added to the label of the tricyclic antidepressant
, according to the FDA.
The latter is a tricyclic antidepressant
that inhibits the reuptake of noradrenaline, and to a lesser extent, that of serotonin.
Of those children, seven were taking antidepressants: five, a tricyclic antidepressant
; one, venlafaxine; and one, mianserin.
No Food and Drug Administration-approved tricyclic antidepressant
in the Tufts review showed a low potential risk of carcinogenicity (defined as no positive preclinical or clinical studies or only negative studies).
His first line for treating constant neuropathic pain is a tricyclic antidepressant
or venlafaxine, followed by an anticonvulsant drug or bupropion.