neuroma

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  • noun

Words related to neuroma

any tumor derived from cells of the nervous system

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Traumatic neuroma: unusual benign lesion occurring in the mastectomy scar.
Peripheral nerve tumors that may manifest in oral cavity includes several differentials such as schwannoma (also known as neurilemmoma or peripheral nerve sheath tumor), neurofibroma, neurinoma in association with multiple endocrine neoplasia, palisaded encapsulated neurinoma, traumatic neuroma and granular cell tumor.2,5 Immunohistochemical reactivity against S-100 and neuron-specific enolase is an essential tool to differentiate these tumors from spindle cell neoplasms of other origin (myofibroblastic tumors, tumors of muscle tissue origin, and fibroblastic tumors).
Traumatic neuroma closely mimics the histological picture but can be ruled out by the presence of inflammatory cells and scarring.
(31-33) This imaging modality has been successfully applied for the diagnosis of the formation of traumatic neuromas, which are non-neoplastic masses of proliferating cells that include fibroblasts, neurons and Schwann cells.
Traumatic neuromas may occur in the stump of the cystic duct after a cholecystectomy.
The traumatic neuroma is a non-neoplastic lesion characterized by the proliferation of schwann cells and nerve fibers that arise following injury to a nerve.
Traumatic neuroma was first described in 1811 by Odier as an enlargement or swelling that developed at the distal end of the proximal segment of the peripheral nerve after a partial or complete cut.
Unilateral or localized intramandibular canal lesions such as solitary neurofibromas [29,30], traumatic neuroma of the inferior alveolar nerve [31], localized hypertrophic neuropathy (intraneural perineurioma) [32], vascular leiomyoma [23], and schwannomas were excluded [15] after CT examination.
(8) Both clinically and histologically confusing was patient 7 with a proximal traumatic neuroma, a lesion that differs from peripheral nerve traumatic neuromas by its lack of collagen and densely packed disorganized nerve fiber (9) (Figure 1, D).
Ameloblastoma has been reported to occur with calcifying odontogenic cyst, (10) traumatic neuroma, (11) aneurysmal bone cyst, (12) osteogenic sarcoma, (13) basal cell nevus syndrome, (14) glandular odontogenic cyst, (15) osteoblastoma, (16) and squamous cell carcinoma.
On the other hand, granular cell changes have been repeatedly reported in sites of previous surgical trauma.[2,3] It has been highlighted that in some cases associated with surgery, the tumor shows features of both granular cell tumor and traumatic neuroma. Such lesions recently have been labeled granular cell traumatic neuroma in an article published in the ARCHIVES by Rosso et al,[4] who found some examples in mastectomy scars.
Traumatic neuromas usually follow an injury and have an irregular disorganized architecture consisting of a proliferation of individual nerve fascicles separated by a fibrotic, sometimes inflamed, stroma.