thiotepa


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Related to thiotepa: busulfan
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Words related to thiotepa

an antineoplastic drug used to treat certain malignancies

References in periodicals archive ?
The superiority of any of the IVCT agents (mitomycin C, epirubicin, pirarubicin, and thiotepa) to one another has yet to be demonstrated (29).
The recently published trial assessed the tolerability and efficacy of adding rituximab with or without thiotepa to methotrexate-cytarabine combination therapy (the MATRix regimen), followed by a second randomization comparing consolidation with whole-brain radiotherapy or autologous stem cell transplantation in patients with primary CNS lymphoma.
The options of (A) conditioning with alemtuzumab, treosulfan, fludarabine, and thiotepa using a TCR-alpha and -beta depleted graft versus (B) using a T-cell replete marrow graft after cyclophosphamide 14, 5 mg/kg days -6 and -5, flu 30 mg/[m.sup.2] days -6 to -2 (5 days), and 200 cGy TBI day -1 [15] with the addition of busulfan 3.2 mg/kg/day, days -4 and -3 to achieve myeloablation [16] as conditioning and posttransplant cyclophosphamide 50 mg/kg days +3 and +4 and tacrolimus and mycophenolate mofetil as graft-versus-host-disease (GVHD) prophylaxis [15] were discussed.
Huitema, "Altered cyclophosphamide and thiotepa pharmacokinetics in a patient with moderate renal insufficiency," Cancer Chemotherapy and Pharmacology, vol.
[20] HDCT: [greater than or equal 821 months to] 1 cycle carboplatin + etoposide [+ or -] ifosfamide, thiotepa, or cyclophosphamide Author PFS/EFS OS (Year) Beyer HR HR et al.
Patients receiving Grifola had a lower recurrence rate than other patients who instead received either BCG, mitomycin C, thiotepa, or placebo.
- Thiotepa is now available through US-based generic pharmaceutical manufacturer Amneal Biosciences in both 100 mg/vial and 15 mg/vial as branded Tepadina (thiotepa) for injection, the company said.
The various adjunctive treatments include topical corticosteroids, beta irradiation, argon and excimer laser, thiotepa, mitomycin C, etc.
Zhang et al., "Prospective study of cyclophosphamide, thiotepa, carboplatin combined with adoptive DCCIK followed by metronomic cyclophosphamide therapy as salvage treatment for triple negative metastatic breast cancers patients (aged <45)," Clinical and Translational Oncology, vol.
Zaloudek and Norris described a 16-year-old patient with stage Ia poorly differentiated SLCT with RMS elements who was treated with USO and later thiotepa and 5-fluorouracil after recurrence at 1.4 years.
A 32-year-old man with a history of acute myelogenous leukemia (AML) secondary to myelodysplastic syndrome underwent double umbilical cord allogeneic SCT after fludarabine (Flu), cyclophosphamide (Cy), thiotepa, and total body irradiation (TBI) conditioning 6 months after his AML diagnosis.
No standardization of the use of adjunctive chemotherapy or regimens have been agreed upon, but agents reported include cisplatin, gemcitabine, 5-FU, mitomycin, adriamycin, thiotepa, fluoxymesterone, carboplatin, paclitaxel, docetaxel, and VP-16 [1, 4, 7,14].
Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N',N"-triethylenethiophosphoramide (thiotepa) and NN'N"-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
A study on the effect of thiotepa on mice spermatogenesis using light and electronic microscope.