This is an important point because several researchers have noted that initial acquisition in the MST is complicated by interfering behaviors, such as thigmotaxis
(circling the circumference of pool) and failing to climb onto the platform when it is reached (Cain et al.
Zhang, "Bright lighting conditions during testing increase thigmotaxis
and impair water maze performance in BALB/c mice," Behavioural Brain Research, vol.
In open field test, natural tendency of a rodent, named as "thigmotaxis
", is to prefer the peripheral zone and walk close to the walls (Treit and Fundytus 1988).
As expected, parallel results were obtained for the time spent in the periphery; sildenafil treatment reduced thigmotaxis
relative to control animals (data not shown).
Each audience member will have a viewer for participating in the screening of three original works, such as "Lucifugia Thigmotaxis
," about a cockroach named Stanley.