JNC VI specifically states that in the treatment of hypertension in the elderly, "thiazide
diuretics or beta-blockers in combination with thiazide
diuretics are recommended because they are effective in reducing morbidity and mortality in older persons with hypertension as shown in multiple randomized controlled trials.
Regarding antihypertensive drug selection, the new statement endorses a focus on treating hypertensive patients with established coronary artery disease with a beta-blocker, a renin-angiotensin-aldosterone system blocker such as an ACE inhibitor or angiotensin-receptor blocker, and a thiazide
Harper will often prescribe a thiazide
or loop diuretic to help with the excretion of potassium.
Throughout the trial, an average of 50% of patients in the amlodipine arm were on both amlodipine and perindopril, and an average of 55% in the atenolol arm were on atenolol and the thiazide
A patient started on a thiazide
diuretic should be weighed 48 hours after therapy is initiated.
In the investigation, [beta]-blockers--alone or in combination with thiazide
diuretics--were associated with a significantly decreased fracture risk, said Raymond G.
The sixth application relates to "Compositions and Methods Comprising a Thiazide
Diuretic and a Mineralocorticoid Inhibitor.
With respect to diuretic use, risks associated with thiazide
and nonthiazide diuretic use were also assessed separately, but neither was associated with breast cancer risk," they said.
Hypertension is prevalent in gout patients and they are often treated with anti-hypertensive agents such as thiazide
For example, patients with recurrent calcium nephrolithiasis may benefit from a thiazide
diuretic or indapamide to treat both the hypertension and prevent future calculi if they are a hyperexcretor of calcium.
SAN FRANCISCO -- Common drugs such as thiazide
diuretics, glyburide, and celecoxib can be used safely by most patients who previously had a reaction to sulfonamide antibiotics, Dr.
As described in the current JNC-7 hypertension treatment guidelines, if SBP is 20 mmHg or DBP is 10 mmHg above a patient's goal, consideration should be given to initiating therapy with two antihypertensive drugs, one of which is usually a thiazide
The diabetes-causing potential of beta-blockers and thiazide
diuretics can in some cases be avoided by using alternative drugs.
Systemic Lupus Erythematosus Thiazide
diuretics have been reported to cause exacerbation or activation of systemic lupus erythematosus.
In breast-feeding patients, thiazide
diuretics should not be used; furosemide is safe, he said.