(22,23) Intermittent terbinafine
dosing is as effective as continuous dosing and is the study author's preferred regimen.
While prolonged treatment is required in any case, terbinafine
may produce results in about 3 months, whereas griseofulvin may require up to 9 months of therapy.
MOB-015 is an internally developed topical formulation of terbinafine
for the treatment of onychomycosis, currently under clinical development in phase 3.
This isolate was susceptible to terbinafine
(MIC = 0.008 mcg/ ml) and griseofulvin (MIC = 1 mcg/ml).
Since all the patients had body surface involvement of around 30% they were started on topical terbinafine
cream, twice daily for 4 weeks.
Key words: aspergillosis, itraconazole, voriconazole, terbinafine
, subcutaneous implant, avian, Japanese quail, Coturnix japonica
Yeast was sub cultured on three Petri dishes to assess the antifungal activity of extracts of Aloe vera, Cymbopogon citratus and terbinafine
by disc diffusion method.
Of these 16 cases, five occurred during current use of oral antifungal agents: two were using ketoconazole, two were using itraconazole, and one was using terbinafine
. Out of the ten remaining cases, only one had a history of using an antifungal agent while the other nine cases occurred before the use of any antifungal agent.
Notably, it should be noted that the reference drugs, ketoconazole and terbinafine
, were unable to inhibit the fungal growth of these strains at concentrations of 640 [micro]g [L.sup.-1] and 480 [micro]g [L.sup.-1], respectively.
prolificans after five days necessitating the commencement of Voriconazole and Terbinafine
 In this article, we are reporting a case of AGEP caused by terbinafine
Objective: To make a comparison between terbinafine
1% cream and ketoconazole 2% cream in the treatment of pityriasis versicolor.
The treatment under study, MOB-015, is a proprietary topical formulation of terbinafine
, which was developed by Moberg Pharma and is the most widely used oral prescription treatment for onychomycosis.
The minimal inhibitory concentrations (MICs) of fluconazole (Sigma Aldrich, USA) and terbinafine
(Biomole, USA) against all the five strains (as above) were determined by broth microdilution method as per guidelines of CSLI (formerly NCCLS) (12) using RPMI 1640 (Sigma Aldrich, USA) buffered with MOPS (Sigma Chemical Co.) in 96-well tissue culture plates with positive and negative growth as well as drug controls.
is a good choice to decrease severity of SD.