succinic acid

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  • noun

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a dicarboxylic acid (C4H6O4) active in metabolic processes

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References in periodicals archive ?
has issued a voluntary nationwide recall of ten lots of Methylprednisolone Sodium Succinate for Injection, USP, 40mg, 125mg, and 1g, the company said.
Transplanting NSCs and iNSCs directly into the cerebrospinal fluid reduces the amount of succinate, reprogramming the macrophages and microglia--in essence, turning bad immune cells good.
For the 12 months ended September 2017, total US sales at Average Wholesale Price (AWP) of Metoprolol Succinate extended release tablets 25 mg, 50 mg, 100 mg and 200 mg were approximately USD690m, according to IMS.
For every two acetyl-CoA molecules directed to the glyoxylate cycle, there is a net production of one succinate molecule, which corresponds to half the acetyl-CoA amount, so that n/4 succinate molecules are produced.
3) These data are concordant and consistent with the succinate findings in the 2014 Nature report.
The paraganglioma syndromes caused by mutations of the succinate dehydrogenase (SDH) genes make up most of the familial cases.
Thermal decomposition temperatures of the starch succinate (SS) and cross- linked starch succinate (CLSS) were analyzed using TA Instruments equipped with a thermo-balance (SDT Q600 USA).
A 2013 stratified subset meta-analysis used data from landmark randomized controlled trials (RCTs) that evaluated beta-blockers vs placebo in patients with systolic heart failure to compare metoprolol succinate (MERIT-HF) vs placebo with bisoprolol (CIBIS-II), carvedilol (COPERNICUS), and nebivolol (SENIORS-SHF) vs placebo (table).
The second group included 13 patients with pathospermia complicated chronic bacterial prostatitis who, along with the conventional therapy, received ethylmethylhydroxypyridine succinate (daily dose 125 mg) for 4 weeks, and then were treated with unspecific stimulation of spermatogenesis similar in duration and content.
Succinate as an ingredient is more prone to have allergic reaction as compared to Sodium phosphate, because of high affinity of succinate esters to different serum proteins, and this could favour the immunogenic role of succinates and may promote an IgE mediated reaction.
The Dow Chemical Company and Cambrex have completed and opened the operational facility for Dow's Hydroxypropyl Methylcellulose Acetate Succinate (HPMCAS) for Drug Solubility Enhancement.
developed a propylene random copolymer suitable for injection stretch blow molding with a wider processing window using a Ziegler-Natta catalyst with a succinate internal donor.
The metabolites of anaerobic fungi have so far been reported as formate, acetate, lactate, ethanol, succinate, C[O.
Hallgreen R-8010 is a bio-based polymeric succinate that is said to improve the flexibility and pliability of biopolymers including polylactic acid (PLA), starch-based polymers, polyhydroxyalkanoate (PHA) and polyhydroxybutyrate (PHB), while maintaining long-term compatibility.