succinic acid

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a dicarboxylic acid (C4H6O4) active in metabolic processes

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Patent and Trademark Office has granted Achieve a patent on succinate salt of cytisinicline and use thereof.
Meglumine sodium succinate - solution for infusion, 15 mg / ml 200 ml.
The company added that the Solifenacin Succinate tablets is the generic version of Astellas Pharma's product VesiCare.
(18) It is a key respiratory enzyme linking the Krebs cycle and electron transport chain, whose function is to catalyze the energy-dependent conversion of succinate to fumarate.
The purpose of this study was to explore the clinical efficacy and safety of the use of methylprednisolone succinate in our patients admitted with cervical spine cord injury having incomplete paralysis.
Metabolic engineering of succinate producing strains such as Actinobacillus succinogenes (5,6), Manheimia succiniproducens (7), Anaerobiospirillum succiniproducens (8), recombinant Escherichia coli (9,10), Corynebacterium glutamicum (11,12,13), Saccharomyces cerevisiae (14,15,16) were carried out leading to commercialization of the fermentation processes using the mutant strains (17,18).
The rest of the 5% of the tumors were previously thought to be wild type tumors, but now they include tumors with mutations in succinate dehydrogenase-B (SDH-B) and BRAF.
All the pyogenic abscesses in our study showed cytosolic branched chain amino acid, lactate, alanine, acetate and one of them showed succinate peak.
Transplanting NSCs and iNSCs directly into the cerebrospinal fluid reduces the amount of succinate, reprogramming the macrophages and microglia--in essence, turning bad immune cells good.
The plasma concentrations of most energy metabolism intermediates were significantly higher in PAD patients than those in the control group, with the exceptions of fumarate, lactate, and succinate, that were decreased (Figure 1(a)).
The term oncometabolites refers to intermediates of metabolism that abnormally accumulate in cancer cells upstream (e.g., L-2-hydroxyglutarate, succinate, fumarate) or downstream (e.g., D-2-hydroxyglutarate) of metabolic defects, often through loss-of-function or gain-of-function mutations, respectively, of genes encoding the corresponding enzymes.
Under the conditions of high flux from succinate oxidation and high proton motive force, the electrons can backflow to NDH and escape at the level of Q site ([I.sub.Q]) towards the molecular oxygen [30,31].
9,161,896 B2) for a cosmetic that is comprised of an organic acid selected from the group consisting of n-octadecenyl succinic acid cholesteryl monoester, n-hexadecenyl succinic acid cholesteryl monoester, cholesterol hydrogen succinate and mixtures thereof; a base; ceramide; water; and an acid other than the first component.
The latter produces glyoxylate and succinate in the reaction catalyzed by isocitrate lyase.