melanoma

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Related to subungual melanoma: Acral lentiginous melanoma
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  • noun

Synonyms for melanoma

any of several malignant neoplasms (usually of the skin) consisting of melanocytes

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"While subungual melanoma is not as common as other forms of skin cancer, it does tend to afflict certain ethnic groups more than others," explains Dr.
Defined as skin cancer originating beneath the fingernail or toenail, subungual melanomas are rare and may be difficult to identify.
The signs cited as indicative of early subungual melanoma are a hyperpigmented streak wider than 6 mm, dystrophic changes of the nail, its onset after middle age, and the expansion of dark pigmentation from the band of LM into the adjoining cuticle and proximal or lateral nailfolds (Hutchinson's sign).
Subungual melanoma: a clinico-pathological study of 24 cases.
Two features which lead to suspicion of subungual melanoma are the associated pigmentation of the adjacent nail fold (Hutchinson's sign) and progressive elevation of the nail from the nail bed.
Yet subungual melanoma can be a challenge to diagnose in older African American patients, who commonly have benign linear nail streaks that may be brown or even dark brown.
Her survey found that overall, just one in four (24.8%) of respondents knew of the mnemonic for subungual melanomas.
The role of trauma in subungual melanoma is controversial.
While public awareness of cutaneous melanoma has been increasing, subungual melanoma remains obscure.
"When it's melanoma, patients often present with late-stage disease, because there is frequently a delay in the correct diagnosis," she warned, adding that late-stage subungual melanoma carries a 5-year survival rate of 16%-61%.
"When it's melanoma, patients often present with late stage disease, because there is frequently a delay in the correct diagnosis," she warned, adding that late-stage subungual melanoma carries a 5-year survival rate of 16%-61%.
Lesions that can mimic the nail streaks of subungual melanoma include benign melanocytic nevi and nonmelanocytic tumors such as keratoacanthomas (Dermatol.
Each streak should be examined, however, because darker-skinned individuals have a higher risk of subungual melanoma than light-skinned patients, Dr.
Subungual melanoma is nearly as common in African Americans as it is in white patients, noted Dr.
SAN DIEGO -- Of the many cases of longitudinal melanonychia--a longitudinal brown-black discoloration of the nail plate--only a fraction are subungual melanomas.