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In an attempt to further characterize the spindle cell sarcoma mass, immunohistochemical analysis was performed for osteocalcin and osteonectin.
11,12) As with highgrade round cell sarcomas and spindle cell sarcomas, a number of these neoplasms, which did not contain a translocation identifiable by FISH, were classified as low-grade myxoid neoplasm, not otherwise specified.
Although radiographically and histologically similar to the other spindle cell sarcomas, leiomyosarcoma is immunohistochemically distinct.
Ultra-sound guided biopsy was subsequently conducted which indicated the lesion was a high-grade spindle cell sarcoma.
5 is a useful marker in confirming the neural origin of a spindle cell sarcoma.
Radical subtotal gastrectomy was performed, based on the pathologic diagnosis of spindle cell sarcoma from gastroscopic biopsy specimens.
Distinct areas of rhabdomyosarcoma, liposarcoma, and spindle cell sarcoma with features of malignant pheripheral nerve sheath tumor were indentified (figure 2, a through d).
These characteristics make it difficult to distinguish MPNSTs from other spindle cell sarcomas such as fibrosarcoma, leiomyosarcoma, monophasic synovial sarcoma, etc.
Leiomyosarcomas can be confused histologically with other spindle cell sarcomas, especially fibrosarcomas, malignant schwannomas, and malignant fibrous histiocytomas.