Trefoil' disulphide loop structures as a common feature in breast cancer associated peptide (pS2) pancreatic spasmolytic
polypeptide (PSP), and frog skin peptides (spasmolysins).
One such drug is Buscopan, which by its spasmolytic
action helps in cervical dilatation and additionally considered to decrease pain.
Hyoscine butyl bromide is a quaternary ammonium derivative; it is spasmolytic
for the smooth muscle of the biliary, gastrointestinal and genitourinary tracts.
Phthalides and other constituents from Ligusticum porteri; sedative and spasmolytic
activities of some natural products and derivatives," Natural Product Research 25, no.
integerrima possessed spasmolytic
activity against histamine-induced contraction.
Thyme (19) and juniper (20) are utilized for their carminative, digestive, diuretic, and spasmolytic
tuberosa, has hypothermic, spasmolytic
, hypotensive and antiarrhymatic activities (Vidhya and Nishteswar, 2015).
5) In Iranian folk medicine, caraway has been indicated for gastrointestinal upsets (carminative, spasmolytic
, and anti-flatulence), fever, colds and coughs, menstrual disorders, breast-milk stimulation, and pain relief.
Rooibos tea, Fabaceae) is reported to possess spasmolytic
, airways relaxation, hypotensive and vasodilatory effects, occurred via predominant K+ channel activation and weak Ca++ channel blockade mechanisms (Gilani et al.
repens presented spasmolytic
effect of methanol extract and fractions, on isolated rat ileum (Garin-Aguilar et al.
Evaluation of a spasmolytic
cocktail to prevent radial artery spasm during coronary procedures.
and antiinflammatory effects of Aloysia triphylla and citral, in vitro and in vivo studies.
This combined synergistically with the anti-inflammatory actions of Zingiber officinale (ginger, fresh rhizome x 1 heaped tablespoon) which also exhibits powerful antiemetic, carminative (12) and spasmolytic
Monoterpens known widely used as an antiseptic, axpectorant, spasmolytic
, anesthetic, and sedatives.
Research on trefoil factor family (TFF) peptides started in 1982, when pancreatic spasmolytic
polypeptide, today known as TFF2, and sP2 peptide, today known as TFF1 were discovered .