gastric carcinoma is a rare tumor that is increasing in incidence in an era of risk modification for other forms of gastric adenocarcinoma.
Although cases of the signet-ring cell
variant are exceedingly rare, our patient's meaningful treatment response highlights our unique diagnostic approach and challenges the notion that this cancer is resistant to chemotherapy.
lymphoma of the thyroid: a case report.
Microscopic examination of both specimens revealed mucin-producing malignant cells that were compatible with metastatic mucinous signet-ring cell
adenocarcinoma (figure 2).
The incidence of signet-ring cell
colorectal carcinoma increased by about 4.
Pathologic examination of the cardiac metastasis demonstrated signet-ring cells
, which were histologically different from those of the previous colon cancer.
primary colorectal signet-ring cell
carcinoma: study matched for age, gender, grade, and stage.
While the first area showed only benign fibrocystic tissue, the second was found to be moderately differentiated invasive cluctal carcinoma with a lobular growth pattern and signet-ring cell
features (Fig 3).
The carcinomatous component was subtyped into signet-ring cell
type and nonsignet-ring cell type based on the predominant component (>50% of carcinomatous component).
CT features of primary colorectal signet-ring cell
Primary signet-ring cell
carcinoma of the cervix is exceedingly rare (20,256-258) and it should always be a diagnosis of exclusion.
5% to 2% of all epithelial bladder tumours and primary signet-ring cell
carcinoma, a variant of adenocarcinoma, is extremely rare with a prevalence estimated at 0.
Ten cases (67%) were graded as well or moderately differentiated and 5 (33%) as poorly differentiated with signet-ring cell
morphology showing features of "poorly cohesive carcinomas" per World Health Organization 2010 guidelines.
23-29) Yoshida et al (28) found that the most powerful histologic indicator of ALK rearrangement by multivariate analysis was the presence of solid signet-ring cell
pattern and a mucinous cribriform pattern, which they found to be at least focally present in 78% of [ALK.
A biopsy was performed and this central mass was initially diagnosed as an invasive, poorly differentiated carcinoma with features suggestive of diffuse gastric carcinoma, signet-ring cell