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  • noun

Words related to self-renewal

the act of renewing yourself (or itself)

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NSCs undergo a self-renewal process to maintain their population, as well as differentiate to give rise to all neural cell types: neurons, astrocytes and oligodendrocytes
At the same time, self-renewal keeps the stem cell pool replenished.
A key finding was that the researchers could block cancer cell self-renewal in the MYCN cells by blocking heme synthesis.
The research team also discovered that specialized types of endothelial cells serve as that nurturing environment, known as vascular niche cells, and they choreograph the new converted HSCs' self-renewal.
Morrison and Zhu's laboratories both studied molecules at different ends of the same pathway--one that regulates stem cell self-renewal and tissue regeneration by modulating the expression of a network of RNA-binding proteins.
Spermatogenesis is a complex and tightly-regulated process of cell proliferation and differentiation leading to production of mature spermatozoa from Spermatogonial Stem Cells (SSCs) The coordination of SSCs self-renewal and differentiation is regulated by growth factors produced by somatic cells surrounding SSCs, particularly Sertoli cells (1).
MSCs undergo self-renewal and can be efficiently differentiated into bone, adipose, and cartilage tissue.
Sharpening the saw is the key to continuous personal and professional improvement through self-renewal and self-examination.
Biology of Adult Mesenchymal Stem Cells : Regulation of Niche, Self-Renewal and Differentiation.
However, new evidence in a mouse model shows that spiral ganglion stem cells present in the inner ear are capable of self-renewal and can be grown and induced to differentiate into mature spiral ganglion cells as well as neurons and glial cells.
Now a multi-disciplinary team at the University of Nottingham has created a new stem cell microenvironment which they have found has allowed both the self-renewal of cells and then their evolution into cardiomyocyte (heart) cells.
Very recently, studies by Lonardo and colleagues showed that the Nodal/activin signaling axis drives the self-renewal of pancreatic CSCs, which is not exclusively autocrine but rather relies on an intricate interplay between pancreatic stellate cells as a supportive environment and CSCs (4).
According to the original publication describing the technology, in defined xeno- and feeder-free culture systems, iMatrix-511 supports strong adhesion to hESCs and hiPSCs, long-term self-renewal, and rapid expansion of disscociated hiPSCs.
Spermatogonial stem cells (SSCs) provide the foundation for spermatogenesis that begins with self-renewal and differentiation of spermatogonial stem cells (SSCs) (1).
This Trop2 division promotes self-renewal of the cancer cells, resulting in tumor growth.