However, large community-based drug treatments have been applied with very little success (2) since even a small number of individuals left untreated can pass schistosome
eggs back into the water, maintaining high rates of reinfections (2).
A brief review of the application of proteomics to the identification of novel schistosome
candidate vaccines was recently published (12).
Life history of Heterobilharzia americana Price 1929, a schistosome
of the raccoon and other mammals in southeastern United States.
Schistosomiasis infection was diagnosed at baseline by the presence of schistosome
eggs in a single sample of urine.
The Schistosoma species that cause disease in man share a common life cycle, differing only in the nature of the intermediate snail host and the morphology of the schistosome
Unfortunately, the long term world wide application of the drug coupled with the discovery of praziquantel-tolerant schistosome
has generated concern over the development of drug-resistant schistosoma strains (Shengliang et al.
LacNAc-containing glycans induce granulomas in an in vivo model for schistosome
egg-induced hepatic granuloma formation.
cercarial dermatitis is another disease manifestation caused by species of Schistosoma.
K11777 deactivates enzymes called cysteine proteases, which a schistosome
needs to digest proteins drawn from human blood.
The particular worm, known as schistosome
, is the cause of the disease Bilharzia which affects up to 250million people in the tropics.
Bilharz named this fluke Distomum haematobium (later designated Schistosoma haematobium as the schistosome
with eggs having terminal spines).
One candidate is the schistosome
oligosaccharide lacto-N-neotetraose, according to Dr.
and pinworms), and 90-100% of blood flukes (i.e., schistosome
An examination of the urine may show the Bilharzial Schistosome