retinoblastoma

(redirected from retinoblastomas)
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Related to retinoblastomas: Retinal cancer, exophytic retinoblastoma
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Words related to retinoblastoma

malignant ocular tumor of retinal cells

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Retinoblastoma, as it is hereditary should have genetic screening and family counselling once a child has been identified with the disease.'
This is a rare subtype comprising 1.5% of all retinoblastomas. It is characterised by a relatively flat infiltration of the retina by tumour cells but without a discrete tumour mass.
Retinoblastoma is the commonest tumor (43% overall and 87% among children).
Retinoblastoma is the most common intraocular malignant neoplasm in children, with most cases initiated by a mutation of the tumor-suppressor gene RB1.
Retinoblastoma is known to be caused by mutations in a single gene, RBI, encoding a tumour suppressor protein (Rb) which stops cells from growing until they are ready to divide.
On the other hand, non-germ-line mutation retinoblastomas (unilateral) are best managed with IAC, if the disease is judged to be beyond control by local treatment modalities such as laser photocoagulation, thermotherapy/cryotherapy, or plaque radiotherapy.
The vast majority of nondiffuse type retinoblastomas appears nodular with calcifications, and presence of these calcifications distinguishes retinoblastoma from other intraocular lesions.
Macroscopicamente los retinoblastomas son tumors blandos y friables, con un patron de crecimiento endofitico (cerca del 60%), en el cual el crecimiento celular se dirige hacia las capas internas de la retina y hacia la cavidad vitrea; y un patron exofitico, con crecimiento celular hacia las capas externas de la retina y expansion por el espacio subretiniano, lo que puede causar desprendimiento de retina y posible invasion a la coroides.
Of the 20 samples analyzed (mean age 4 years and male:female ratio is 2.3:1), 18 were poorly differentiated (PD) retinoblastomas and 2 were well differentiated (WD).
In this case presentation, we report our patient who was diagnosed as having Gorlin-Goltz syndrome with clinical, histopathologic, and radiologic findings because of the rarity of the syndrome, and we aimed to draw attention to its association with retinoblastoma and to BCCs that may develop following radiotherapy.
Mumbai, May 25 -- Some of India's leading eye care experts are gathering in Mumbai coming weekend to discuss "Recent Advances in Retinoblastoma" - a CME organised by the Aditya Jyot Institute of Vision Sciences and Research, the research and development unit of Aditya Jyot Eye Hospital, to be held at the Tata Memorial Hospital on May 27, 2012.
Retinoblastoma is the most common eye cancer that occurs in the retina of infants or young children.
For the first time, preimplantation genetic diagnosis for retinoblastoma has ensured the birth of a healthy infant who does not carry the genetic germline for the devastating disease, reported Dr.
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