Rosen, "Corticotropin releasing factor
type-1 receptor antagonism in the dorsolateral bed nucleus of the stria terminalis disrupts contextually conditioned fear, but not unconditioned fear to a predator odor," Psychoneuroendocrinology, vol.
Assenmacher, "Evidence for basal and stress-induced release of corticotropin releasing factor
in the push-pull cannulated median eminence of conscious free-moving rats," Neuroscience Letters, vol.
Reversal by quercetin of corticotrophin releasing factor
induced anxiety-and depression-like effect in mice.
Urocortins and corticotropin releasing factor
type 2 receptors in the hypothalamus and the cardiovascular system.
Role of stress, corticotrophin releasing factor
(CRF) and amygdala plasticity in chronic anxiety.
Abbreviations: FD, functional dyspepsia; RS, restraint stress; NMS, neonatal maternal separation; ELISA, enzyme-linked immunosorbent assay; ANOVA, analysis of variance; CRF, corticosterone releasing factor
; EMA, European Medicines Agency; SEM, standard error of the mean; ED, effective dose.
Experimental data from rats show that nicotine does not act directly at the hypothalamic paraventricular nucleus the site of the corticotrophin- releasing factor
neurons crucial to the regulation of adrenocorticotropic hormone (ACTH).
Activation of brain corticotropin releasing factor
(CRF) receptors mediates stress-related inhibition of upper GI and stimulation of lower GI motor function through interaction with different CRF receptor subtypes.
coverage% kDa 1 Heat shock protein P08238 6 90 90 2 60 kDa Heat shock P10809 34 61 protein 3 Protein dicaudal D Q96G01 6 111 homolog 1 isoform 1 4 Signal transducer P42224 4 87 and activator of transcription 1-alpha/beta 5 Ras-specific guanine Q86X27 3 65 nucleotide- releasing factor
6 Annexin A5 P08758 24 36 7 Triosephosphate P60174 13 26.8 isomerase 8 Interleukin-7 P13232 8 20 9 Glutathione P09211 49 235 S-transferase P 10 Peroxiredoxin-2 P32119 29 22 Spot no.
Studies have shown that T-cells (a type of immune cell that matures in the thymus gland) promote cellular restoration by secreting growth hormone and growth hormone releasing factor
. (5-7) Growth hormone stimulates the growth, reproduction, and regeneration of cells.
Role of thyrotrophin releasing hormone and corticotrophin releasing factor
in stress related alterations of gastrointestinal motor function.
To verify the efficacy of our approach, Androgen Receptor (Exon 1) and Eukaryotic Releasing Factor
3a (Exon 1) genes from a human source and a portion of human Elongation Factor 1a Promoter encompassing 71.8, 75.94 and 60.09% GC bases respectively were chosen for amplification (Table 1).
Circulating growth hormone releasing factor
concentrations in normal subjects and patients with acromegaly.
In recent studies, novel corticotropin releasing factor
(CRF)-related peptides, named Ucn-1, Ucn-2, and Ucn-3 have been identified (1-3).
Currently, the applications for tesamorelin, a growth-hormone releasing factor
, are under review with regulatory agencies in Canada, Europe, Latin America and the Middle East, added the company.