refractory anemia


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Synonyms for refractory anemia

any of various anemic conditions that are not successfully treated by any means other than blood transfusions (and that are not associated with another primary disease)

References in periodicals archive ?
4 Non-diarrheal CD (NDCD) has variable presentation including failure to thrive, short stature, refractory anemia, rickets, vomiting and recurrent oral ulcers.
Abbreviations: RAEB-1/-2, refractory anemia with excess of blasts-1/-2; RCUD, refractory cytopenia with unilineage dysplasia; RCMD, refractory cytopenia with multilineage dysplasia.
The findings are consistent with a highgrade myelodysplastic syndrome, best classified as refractory anemia with excess blasts-2 (RAEB-2) on the basis of the blast count and presence of myelodysplasia.
Refractory anemia leading to renal hemosiderosis and renal failure.
Of the nine cases of myelodysplastic syndrome four were refractory anemia, two were refractory cytopenia with multilineage dysplasia, one was refractory Anemia with Ring sideroblast and two cases of refractory Anemia with excess blasts which compares with the similar study conducted in India 4.
44) Similar benefits were found in a small group of MDS patients with refractory anemia in 2002.
S Food and Drug Administration (FDA) on May 2, 2006 for the treatment of patients with myelodysplastic syndromes (MDS) including previously treated and untreated, de novo and secondary MDS of all French-American-British (FAB) subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, and chronic myelomonocytic leukemia), and Intermediate-1, Intermediate-2, and High-Risk International Prognostic Scoring System (IPSS) groups.
12) As a subgroup of the myelodysplastic syndromes, CMML shares the characteristics of trilineage dysplasia with refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, and refractory anemia with excess blasts in transformation.
Factors that should be addressed include infection, inflammation, malignancy, secondary hyperparathyroidism, blood loss, hemolysis, iron deficiency, bone marrow dysplasia, refractory anemia due to nonrenal conditions, aluminum toxicity, vitamin deficiencies, and concomitant medications that may affect production of red blood cells.
The company is leading the translation of RNAi as a new class of innovative medicines with a core focus on RNAi therapeutics for the treatment of genetically defined diseases, including ALN-TTR for the treatment of transthyretin-mediated amyloidosis (ATTR), ALN-AT3 for the treatment of hemophilia, ALN-PCS for the treatment of severe hypercholesterolemia, ALN-HPN for the treatment of refractory anemia, and ALN-TMP for the treatment of hemoglobinopathies.
They are familial disorders characterized by association of refractory anemia and ineffective erythropoiesis with multinuclearity and karyorrhexis.
This will help to monitor the iron response and evaluate refractory anemia.