refractory anemia


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Related to refractory anemia: Myelodysplastic syndrome, Refractory Anemia with Excess Blasts
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Synonyms for refractory anemia

any of various anemic conditions that are not successfully treated by any means other than blood transfusions (and that are not associated with another primary disease)

References in periodicals archive ?
Significance of p53 overexpression in bone marrow biopsies from patients with bone marrow failure: aplastic anemia, hypocellular refractory anemia, and hypercellular refractory anemia.
Vidaza is approved for the treatment of patients with some of the French-American-British myelodysplastic syndrome subtypes: refractory anemia or refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, and chronic myelomonocyticleukemia.
The postmortem findings were significant for a 90% hypercellular bone marrow with multilineage dysplasia and 15% blasts, suggesting transformation from refractory anemia with ringed sideroblasts to acute myeloid leukemia, or at least refractory anemia with excess blasts (RAEB-2).
One year after diagnosis, laparoscopic splenectomy was done for refractory anemia and thrombocytopenia.
The bone marrow aspirate smear revealed moderate erythroid hyperplasia with severe dysplasia, suggesting a refractory anemia type of myelodysplastic syndrome.
The "Alnylam 5x15" programs include ALN-TTR for the treatment of transthyretin-mediated amyloidosis (ATTR), ALN-AT3 for the treatment of hemophilia, ALN-PCS for the treatment of severe hypercholesterolemia, ALN-HPN for the treatment of refractory anemia, and ALN-TMP for the treatment of hemoglobinopathies.
Dacogen (decitabine) for Injection is indicated for treatment of patients with myelodysplastic syndromes (MDS), including previously treated and untreated, de novo and secondary MDS of all French-American-British (FAB) subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, chronic myelomonocytic leukemia), and Intermediate-1, Intermediate-2 and High-Risk International Prognostic Scoring System (IPSS) groups.