receptor


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Related to receptor: NMDA receptor
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Synonyms for receptor

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Our first step in using a newly discovered receptor gene for drug discovery is the identification of the natural ligand that works on the receptor in the body," said Theresa A.
In separate research, DuPont chemists invented compounds called anthranilic diamides that bind 500 to 2,000 times more readily to the insect receptor than to the mammalian receptors.
Patent 6,756,491, "Steroid-activated nuclear receptors and uses therefore" was issued on 29 June 2004, over 4 months after the publication of our article (Tabb et al.
Presentation Title: Sub-Threshold Doses of Aricept and a Novel 5-HT6 Receptor Antagonist, PRX-07034, Interact To Enhance Memory in the Novel Object Discrimination (NOD) Task
These same receptors can also serve as unintended docking sites for phytoestrogens, weakly estrogenic chemicals produced by plants to deter herbivores, attract beneficial insects, and recruit symbiotic nitrogen-fixing soil bacteria.
Martin predicts that when cadmium binds to the loop between helices 11 and 12 the heat shock proteins are displaced, allowing co-activators to bind, turning the ligand-free receptor into a potent transcription messenger.
This technology enables the delivery of this anti-cancer agent to folate receptors, which are commonly found on tumor cells.
Previous studies have demonstrated that many of these compounds exhibit weak AhR agonist and/or partial antagonist activities in transactivation or receptor transformation assays (Ashida et al.
Our orally-available compound, CCX915, is a highly selective inhibitor of the CCR2 chemokine receptor which is implicated in the damaging inflammation underlying multiple sclerosis and other autoimmune and inflammatory diseases," said Thomas Schall, Ph.
The gonadotropins FSH and LH bind to specific G-protein-coupled receptor sites to stimulate adenylate cyclase and the accumulation of cAMP, which activates enzymes involved in steroidogenesis (Hsueh et al.
Duska is developing a proposed drug, Vagonixen(TM), as a novel treatment of airway disorders, including chronic obstructive pulmonary disorder (COPD), asthma and cough that would block a specific cell surface receptor activated by ATP and thereby alleviate symptoms of these disorders.
The scientists reasoned that if a mouse lacks a particular target of an anesthetic, say a GABA receptor, it should be resistant to the drug's effects.
Global Markets Direct's, 'KiSS-1 Receptor (G-Protein Coupled Receptor 54 or G-Protein Coupled Receptor OT7T175 or hOT7T175 or Hypogonadotropin-1 or Kisspeptins Receptor or Metastin Receptor or KISS1R or GPR54) - Pipeline Review, H1 2016', provides in depth analysis on KiSS-1 Receptor (G-Protein Coupled Receptor 54 or G-Protein Coupled Receptor OT7T175 or hOT7T175 or Hypogonadotropin-1 or Kisspeptins Receptor or Metastin Receptor or KISS1R or GPR54) targeted pipeline therapeutics.
This volume describes receptor design principles and discovery algorithms, and shows how they have been used to produce synthetic receptors for each major class of biomolecules.
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