By placing reasonable detection and feasibility restrictions on these multidimensional spaces (see Supplemental Data in the online Data Supplement), we estimate that we can differentiate at least 10 doubly labeled species, 50 triply labeled species, and 100 quadruply labeled species.
For a proof of principle, we demonstrated that 4c-ALEX can sort and count molecules with different probe stoichiometries and FRET distances by analyzing a solution containing 25 singly, doubly, triply, and quadruply labeled DNA oligonucleotide species (10 pmol/L concentration each; see Table 2 in the online Data Supplement).
Another important note about our practice is that by the time the aforementioned cases reached this paper, they had been quadruply
analyzed and cast through a number of different lenses:
To find quadruply truthfuls I ran a full analysis on them as in the anagram table.
But two of the agreeing cases besides the anagram did show one other coincidence (second 2+2, first 4+4) and so were quadruply truthful, and seven more showed asymmetric or 'half' coincidences.
This study showed in six ways that the anagram's coincidences are real and uncommon: (1) the small number of four term doubly truthfuls (n=n and a=a) out of several hundred equations examined; (2) of the doubles, the small (random?) number that were triply truthful (agreeing in reduced sums); (3) of the latter, the near absence of quadruply truthfuls and (4) the complete absence of other quintruply truthfuls (having more than one additional full coincidence); (5) the failure of all relevant redundant or tautological anagram equations to violate argument 2; and (6, previous section) the failure of other alphabet registers to duplicate the A-1 result.
Inada and Oguri's team found the quadruply
imaged object by sifting through 29,500 quasars in the Sloan Digital Sky Survey.
But without the creative lightning rod of their most immediate predecessor, indie maverick and October Films co-founder Bingham Ray, who left the company late last year, the long-embattled MGM brand will have to work quadruply
hard to define itself.
Blanche's identity in Belle Reprieve is triply (or perhaps quadruply
) embedded: "she" is a woman played by a man who imagines herself not just as Williams's Blanche DuBois, but as Vivien Leigh (like Bette Bourne, a Brit) playing the role of Blanche in Kazan's movie.
Indeed, he regards their failures as quadruply
And as with most social trends, especially the ones involving tomorrow, what is true of the world is doubly true of America, and what is doubly true of America is quadruply
true of Los Angeles.
Two shows, South Coast Repertory's Major Barbara and the Road Theatre Company's The Woman in Black, were quadruply
In addition, two more GRBs may appear within days or weeks from now if GRB 990123 is quadruply