Three double-blinded RCTs studied patients older than 12 years who presented to a family practice clinic complaining of purulent rhinitis
. (4-6) All 3 studies compared amoxicillin treatment with placebo; outcomes were based primarily on patient diaries that recorded symptoms, including nasal discharge.
University of Cape Town Numbers needed Numbers needed Numbers needed to treat to harm Rhinosinusitis (8) 7 190 Common cold & purulent rhinitis
(11) 7 15 12 78 Otitis media (12) 11 24 Acute 11 33 bronchitis ([dagger]) 14 15 ([dagger]) Data combined (19,22) Note: Table made from line graph.
9.2/100 children) and purulent rhinitis
(42/100 children vs.
Poor development of mucous gland in the respiratory and gastro-intestinal tract may result in increased susceptibility to respiratory infections, purulent rhinitis
, dysphonia and diarrhea.
Antibiotic treatment of patients with purulent rhinitis
of less than 10 days duration increased the number of patients who had resolution of the rhinitis 5 days to 7 days later.
Complications of URIs also occurred significantly more often in patients who received placebo rather than Anaferon in otitis media and in purulent rhinitis