Clusters of foamy macrophages are often seen in papillary RCC, metanephric adenoma, and mucinous and tubular spindle cell RCC; and psammoma
body calcifications can be seen in type 1 papillary, chromophobe, and translocation RCCs, and metanephric adenoma.
Matsumura, et al., Update on the potential significance of psammoma
bodies in lung adenocarcinoma from a modern perspective, Histopathology 72 (4) (2018 Mar) 609-618.
Virchow is the first one to describe sand-like granulations in these meningothelial proliferations and had named them "psammoma
body", in 1863 , while Bailey and Bucy had demonstrated their origin from the arachnoid cap cells .
The result showed psammoma
bodies and some heterocyst.
The entire nodule was frozen, and sections showed small, tightly packed tubules and nests of epithelioid cells in a fibrous background notable for many psammoma
bodies (Figure 1).
(1) The pathognomonic histopathologic feature of the psammomatous type is the presence of spherical ossicles, which are similar to psammoma
bodies and cytoplasmic yellow bodies were absent.
In histopathology, micro-calcification is thought to represent psammoma
bodies, which are 10-100 um round laminar crystalline calcific deposits.
The microscopy identified a proliferation depending on tunica vaginalis with papillary architecture and inflammatory cells, fibroblasts, and foaming histiocytes with psammoma
bodies, without atypia, mitosis, and vascular invasion (Figure 2).
No papillary growth pattern, foamy histiocytes, psammoma
bodies, or background of extensive network of thin-walled "chicken-wire" vasculature was identified and no tumour necrosis was seen.
Occasionally, metastases to the breast demonstrate features that lead the pathologist to a correct diagnosis, such as cells with nuclear grooves, intranuclear inclusions, powdery chromatin and psammoma
bodies as seen in our case.
body is seen, and brain tissue is also seen, which is separated with tumor by pia meter.
bodies found in the Pap smear are suggestive of gynaecologic malignancy, and more detailed examination is required.5
bodies, squamous metaplasia, and marked sclerosis were the criteria used to diagnose the diffuse sclerosing variant of PTC (DSVPTC) .
Histopathological investigations of the mass showed a cystic neoplasm composed of various mature tissue components including skin, pilosebaceous glands, well-developed respiratory and gastric epithelium, and glial tissue with numerous psammoma