* Study design: This manuscript represents a descriptive study of the implementation of a novel, evidence-based risk stratification tool for the prophylaxis
of venous thromboembolic disease patients in a single site, dedicated, protocol-driven ED OU.
The impact and benefit of co-trimoxazole prophylaxis
on morbidity and mortality among HIV-infected patients with a CD4+ count [less than or equal to] 350 cells/[micro]L in regions with high infectious disease burdens (irrespective of CD4+ count) have been shown in a good-quality systematic review and meta-analysis that included both randomised controlled trials (RCTs) and observational cohort studies.
In the intraindividual comparison involving 48 participants in group D, the annualized bleeding rate was 68 percent lower with emicizumab prophylaxis
compared with the rate with previous factor VIII prophylaxis
Dentists had inadequate knowledge about existing evidence on antibiotic use in dentistry and endocarditis prophylaxis
in Persons Who Plan to Travel in Areas with High or Intermediate Hepatitis A Endemicity
Conclusions: Our findings suggest that shorter antimicrobial prophylaxis
regimens, using sterile gels and intestinal cleansing may be useful in the control of infections developing after TPB.
A Phase 3 treatment study of Baremsis in around 560 surgical patients who develop PONV and who have not received prior prophylaxis
is ongoing, and Acacia Pharma has already successfully completed two Phase 3 prophylaxis
studies showing that Baremsis is safe and effective at preventing PONV, when given either alone or in combination with other antiemetics, prior to surgery.
The trials comparing tetracycline prophylaxis
with placebo showed significant risk reduction in upper genital tract infection in tetracycline users (up to 88%), with an overall postinfection rate similar to that reported in the United States (<1%).
About one-third of patients presented to a hospital with a clinical pathway--which was associated with a 46% greater likelihood of receiving prophylaxis
but no increase in testing rates--and two-thirds presented to hospitals with a specialized sexual assault evaluation team, which did not significantly impact testing or prophylaxis
Efforts have been undertaken to establish guidelines for the appropriate use of antibiotic prophylaxis
. These guidelines are designed to provide professionals with a standardized approach to rational, safe and effective use of antimicrobial agents for the prevention of SSI, and their content is based on current available clinical evidence, besides emerging issues.
Objective: To compare the effect of antibiotic prophylaxis
with placebo in prevention of wound infection amongst patients undergoing clean open inguinal herniorrhaphy (without mesh).
The commonly used guidelines for VTE risk assessment and prophylaxis
are Caprini's VTE risk assessment model and American College of Chest Physicians (ACCP) consensus guidelines for VTE prophylaxis
The Use of VTE prophylaxis
in relatioN to patiEnt risk profiling (TUNE-IN) Wave 2 study  was conducted to evaluate common practice in the assessment of VTE risk in the inpatient healthcare setting in Gauteng, SA.
 A clinical trial involving more than 16 000 high-risk surgical patients showed the necessity and efficacy of VTE prophylaxis
. In this trial, VTE prophylaxis
was shown to reduce the incidence of acute DVT by 66% and the mortality rate of PE by 50%.