The FDA Breakthrough Therapy Designation was based on clinical data with Janssen's prophylactic
RSV senior vaccine that may demonstrate substantial improvement compared to available standard of care on a clinically significant endpoint(s).2
The company added that the investigational prophylactic
vaccine is currently in a Phase 2b proof of concept study to investigate the safety and efficacy of the vaccine against RSV in adults aged 65 years and older.
"Our data suggest that there is no urgency to insert the filter in patients who can be treated with prophylactic
anticoagulation within seven days after injury," the authors write.
In the absence of contraindications, all patients should be candidates for breast reconstruction in order to minimize the negative physical and psychological impact of the mastectomy; the breast reconstruction should preferably be immediate, performed at the same time of the prophylactic
mastectomy, by a team of dedicated plastic surgeons, or with permanent prosthesis or autologous tissues.
phenylephrine infusion with crystalloid preload was found associated with reduced number of rescue boluses and rescue phenylephrine dose and lesser total intraoperative fluid administration, when compared to preload with rescue boluses.
'These preventive measures include strategies such as distribution of prophylactics
, such as condoms,' she added.
"This pattern and high rate of prophylactic
prescribing indicates a clear overuse of antibiotics," said study author Markus Hufnagel.
In women with a BRCA1/2 deleterious mutation, contralateral prophylactic
mastectomy is expected to improve all-cause mortality [7, 8].
David Lye et al conducted a multicentre, open-label, randomised, superiority trial which included two groups: prophylactic
platelet transfusion plus supportive care (transfusion group) versus supportive care alone (control group).
One approach to preventing infection is the administration of prophylactic
The study included 85 patients, none of whom had been on prophylactic
medication during the previous 3 months.
The published data prompted a Cochrane systematic review which concluded that acupuncture is at least as effective as prophylactic
drug therapy, has fewer adverse effects, and should be considered a legitimate treatment option (Cochrane Database Syst.
SURGERY FOR BREAST CANCER AND ALTERNATIVE TREATMENTS.
gynecologists showed prophylactic
bilateral salpingectomy is catching on when performed in conjunction with hysterectomy, but far less so for tubal sterilization, Dr.
From this, we could work out the proportions of cases in which IV access was established for drug administration, for fluid resuscitation or as a prophylactic