procarbazine


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Words related to procarbazine

an antineoplastic drug used to treat Hodgkin's disease

References in periodicals archive ?
In 2016, Hataet al.,retrospectively analyzed the long-term outcome of a case series (36 patients) with OD treated with RTand procarbazine, nimustine, vincristine (PAV) therapy.3 Their results showed that IDH mutation and 1p/19q loss were the prognostic factors to consider for OD, not WHO grade, furthermore there was a significantly better prognosis for patients with 1p/19q co-deletion.
Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme.
Taphoorn et al., "Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951," Journal of Clinical Oncology, vol.
For instance, procarbazine, an azo derivative, has been part of cancer treatment schemes since its discovery 50 years ago.
De Rooi et al., "Intrinsic molecular subtypes of glioma are prognostic and predict benefit from adjuvant procarbazine, lomustine, and vincristine chemotherapy in combination with other prognostic factors in anaplastic oligodendroglial brain tumors: a report from EORTC study 26951," Journal of Clinical Oncology, vol.
The effect of cyclophosphamide and procarbazine combination on sperm count and hormone levels (FSH) was significant.
The drugs include procarbazine, lumostine, and vincristine.
Antibiotics Doxyrubicin 0 0 Mitomycin C + + + + + + Miscellaneous Dacarbazine + + Hydroxyurea 0 + Procarbazine + 0 Activity against indicated type of organism Antineoplastic Anaerobic Agent bacteria Yeasts Alkylating agents Carmustine 0 [+ or -] Chlorambecil + + Neoplatin ND 0 No activity shown by busulphan, cyclophosphamide, dibromomannitol, and melphalan.
Previous case reports have described treatment with vincristine, lomustine, and prednisone, (4) vincristine alone, (12) and procarbazine, CCNU, and vincristine.
The patient was treated with five cycles of BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone) chemotherapy.
For chemotherapy ABVD (Adriamycin, Bleomycin, Vinblastine, Deticene) was used in 32 patients, ABVD + COPP (Cyclophosphamid, Vincristine, Procarbazine, Prednisone) was used in 3 patients, OPPA (Vincristine, Prednisone, Procarbazine, Adriamycin) + COPP was used in 2 patients, COPP+ABV was used in 3 patients and ARA-C/VP-16 + COPP/ABV + CHOP (Cyclophosphamid, Adriamycin, Vincristine, Prednisone) was used in 1 patient.
The product is intended to treat adult patients that have been recently diagnosed with glioblastoma multiforme, concomitantly with radiotherapy and then as maintenance treatment and also refractory anaplastic astrocytoma patients whose disease has progressed on a drug regimen containing nitrosourea and procarbazine.
The management consisted of urgent establishment of ABVD (adriamycin, bleomycin, vinblastine, dacarbazine) chemotherapy intensified by BEACOPP (bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine=oncovin, procarbazine, prednisone) chemotherapy.
Alkyl-ating chemotherapeutic agents, such as procarbazine and/or cyclophosphamide, cause prolonged azoospermia in 90%-100H of men and premature ovarian failure (POP) in 5%-25% of younger women under 30 years old; however, the risks are low with radiotherapy alone if pelvic radiation or chemotherapy with alkylating agents is not given (22).
An oligodendroglioma with those molecular alterations has a better response to PCV (procarbazine hydrochloride, lomustine [CCNU; CeeNU], and vincristine sulfate) chemotherapy.