According to Table 1 it can be seen that sulfasalazine caused a significant reduction in the number of spermatogonia, primary spermatocytes but Vitamin E and C combined together have significantly increased in all experimental groups compared to the control group (Figures 1 to 5).
Different spermatogenic cells (spermatogonia, primary spermatocytes, early spermatids, late spermatids and spermatozoa) and Sertoli cells were identified according to their distinct morphological characteristics as described by Leme and Papa (2010) and Santos et al.
Lack of UCHL1 decreased apoptosis rate and increased the number of premeiotic germ cells in immature mice (13), but in adult mice spermatogenesis was damaged by spermatogonial reduction and primary spermatocytes which mainly undergo apoptosis (13).
In early recrudescence, primary spermatocytes predominate, whereas in late recrudescence, secondary spermatocytes and spermatids are most abundant; (3) Spermiogenesis, lumina of the seminiferous tubules are lined by clusters of sperm or metamorphosing spermatids.
Because the primary spermatocytes in a cyst undergo two meiotic divisions leading to the formation of a sperm bundle containing four sperm for each spermatocyte, we surmised there would be an unbalanced amount of chromatin material among the sperm nuclei within eupyrene sperm bundles from an [F.