(redirected from presenilin gene)
Also found in: Dictionary, Medical, Encyclopedia.
Graphic Thesaurus  🔍
Display ON
Animation ON
  • noun

Synonyms for gene

References in periodicals archive ?
Presenilin gene mutations promote the breakdown of APP, leading to increased production of harmful beta-amyloid.
Certain mutations in the presenilin genes (PS1 and PS2) cause the most common type of familial early-onset AD (FAD).
In another twist to the garbage disposal story, a University of Pennsylvania team of scientists showed that removing the presenilin genes altogether in transgenic mice also interfered with the cell's lysosomes (Wilson et al.
Over 85 point mutations in the presenilin genes, PS1 and PS2, are known to cause early onset Alzheimer's Disease with 100% penetrance.
Recent AD research has shown that brain cells from people with FAD, or cells into which mutated presenilin genes have been inserted, show alterations in regulation of calcium signaling, a process that is fundamental for normal cellular metabolism.