Amerio P, Tracanna M, De Remigis P et al: Vitiligo associated with other autoimmune diseases: polyglandular
autoimmune syndrome types 3B+C and 4.
Vitiligo-asociated autoimmune polyglandular
Other diseases of connection to Sephardi origin include: Alpha-Thalassemia, Ataxia Telangiectasia, Corticosterone Methyloxidase Type II Deficiency, Costeff Optical Atrophy, Cystic Fibrosis (CF), Familial Creutzfeldt-Jakob Disease, Familial Tumoral Calcinosis (Normophosphatemic Type), Inclusion Body Myophy Type 28, Metachromic Leukodystrophy, Polyglandular
Deficiency Syndrome, Pseudocholinesterase Deficiency, Spinal Muscular Athrophy (S.
Premature ovarian failure associated with autoimmune polyglandular
syndrome: pathophysiological mechanism and future fertility.
Pernicious anemia and hypothyroidism can be associated with FHF due to AIH in the context of polyglandular
autoimmune syndrome, but FHF is unlikely in the other causes.
Classification of the less common types of diabetes mellitus Genetic defect in Beta ([beta]) cells functioning Mitochondrial disorders Late onset diabetes in youth Diseases of the exocrine pancreas Cystic fibrosis-related diabetes Drug-induced diabetes Steroids and chemotherapy drugs Genetic syndromes Prader-Willi, Down, Turner and Wolfram syndromes Endocrine pathologies Cushing and polyglandular
autoimmune syndromes Table modified from Rhodes ET, Ferrari LR, Wolfsdorf JI.
Coverage begins with principles, and growth and maturation, leading into obesity and nutrition, diabetes mellitus, the parathyroid gland, calciotropic hormones, and bone metabolism, and coverage of the thyroid, adrenal gland, and cardiovascular system as well as endocrine changes in critically ill patients, reproductive endocrinology and sexual function, polyglandular
syndromes, and testing.
In general, hypothyroidism discovered before the age of three is considered to represent a failure of newborn screening, though cases associated with a rare disease of the endocrine system called polyglandular
autoimmune syndrome have been reported.
syndrome type 1 (autoimmune polyendocrine-candidiasis-ectodermal dystrophy; APECED), a rare autosomal recessive condition, in which incidence of autoimmune endocrine diseases of the parathyroid, thyroid, pancreas and adrenal is increased (9).
deficiency--This makes the body deficient in multiple hormones.
Coincidental presentation of vitiligo and psoriasis in a patient with polyglandular
Certain dermatoses with underlying pathogenesis like vitiligo are known to occur in DM as a part of polyglandular
If adrenal autoantibodies are detected, the presence of an autoimmune polyglandular
syndrome should be entertained.
Hashimoto disease is observed with a rate of 10% and type 2 DM is observed with a rate of 70% as a component of type 1 autoimmune polyglandular