The researchers have found that pneumococcus
and other bacteria accomplish this by targeting a key component of the immune system - the inflammasomes.
Streptococcus pneumoniae (pneumococcus
) is a bacterium frequently found in the upper respiratory tract of healthy children and adults, and can cause serious infections ranging from pneumonia, meningitis, and sepsis, representing a major global health problem.
"It is unclear if completely reducing the spread of pneumococcus
in children is the best thing."
According to oral penicillin MIC values, 39 pneumococcus
strains (48.75) showed low-level resistance to penicillin.
The risk of pneumonia related mortality increases three fold if pneumonia is due to Pneumococcus
Results: Of the 93 patients with SCD 21.5% (n=20) were vaccinated against pneumococcus
and 21.5% (n=20) were regularly vaccinated against influenza.
The prevalence of penicillin-resistant pneumococcus
strains varies considerably between states (7,8).
Streptococcus pneumoniae, the pneumococcus
, is thought to be responsible for at least half of all community-acquired pneumonia and otitis media and remains a significant cause of bacteremia and meningitis .
This is a follow-on investment from the foundation for achievement based on the development of a new pneumococcal vaccine, which targets Streptococcus pneumoniae (pneumococcus
) towards clinical testing.
The Center for Disease Control and Prevention (CDC) of the United States, in their vaccination schedule for 2013, recommends that people over 60 should be vaccinated against influenza, Diphtheria, Pertussis, Tetanus (DPT) and, Herpes Zoster and in individuals over 65 years also against Pneumococcus
Beginning Sunday, the Ministry of Health will carry out a three-month vaccination campaign against pneumococcal disease, an infection caused by streptococcus pneumonia bacteria ("pneumococcus
Most recently, he was director of the Vaccine Development Global Program at PATH, where he built and advanced the development of vaccines against pneumococcus
, rotavirus, ETEC, shigella, meningococcus, influenza, respiratory syncytial virus, polio and Japanese encephalitis.
My group has been studying the details of the interaction between flu virus and pneumococci to unravel the steps in the dance between the flu virus and the pneumococcus
in the nasopharynx that results in significant respiratory diseases.
In 2008, there were an estimated 203,000 deaths due to Haemophilus influenzae type b (Hib) and 541,000 deaths due to Streptococcus pneumoniae (pneumococcus
) in children under five.