Malignant Epithelial Cells arranged Singly and in Clusters with Mild Pleomorphism
(FNAC-Pap Stain) 10X
Most importantly, nuclear pleomorphism
, subtle nuclear irregularity, and focal perinuclear haloes are frequently present (Figure 3, B).
Spindle cells showed some atypical features like cellular pleomorphism
and nuclear hyperchromatism.
and polymegathism indices did not differ among keratoconic eyes with different stages and thickness values (p>0.
The International Society of Urological Pathology grading system for clear cell and papillary renal cell carcinoma (3) Grade Description 1 Nucleoli absent or inconspicuous and basophilic at x400 magnifcation 2 Nucleoli conspicuous and eosinophilic at x400 magnifcation, and visible but not prominent at x100 magnifcation 3 Nucleoli conspicuous and eosinophilic at x100 magnifcation 4 Extreme nuclear pleomorphism
and/or multinucleated tumor giant cells and/or rhabdoid and/or sarcomatoid differentiation
Fibrosarcoma shows a herring-bone-like growth pattern, denser cellularity, greater nuclear pleomorphism
, higher mitotic counts and lacks abundant collagen bands.
The cellular morphology includes nuclear pleomorphism
with mitotic figures.
NUMEROUS KERATIN PEARLS AND FEW MITOTIC FIGURES WITH CELLULAR AND NUCLEAR PLEOMORPHISM
AND HYPERCHROMATISM WEREALSO SEEN, ADIAGNOSIS OF WELL-DIFFERENTIATED SQUAMOUS CELL CARCINOMA WAS GIVE (H&E 20X).
They described a type of tumor, found in twelve patients, expressing great pleomorphism
, to which it owes its name.
The purpose of the study was to investigate the changes in the endothelial cell count and cell's polymegathism and pleomorphism
after selective laser trabeculoplasty (SLT) in open-angle glaucoma (OAG).
The light microscopic examination revealed squamous cell carcinoma (SCC) as acanthotic squamous epithelium with deep rete pegs, epithelial and keratin pearls, pleomorphism
, stromal infiltration and hyperchromatic nuclei (Fig.
HandE stained microscopic glass slides were reviewed by two pathologists and were analyzed for various histological features including growth pattern, architecture, neurofibrillary matrix, rosettes, nuclear pleomorphism
, nucleoli, mitotic activity, necrosis and calcification.
Malignancy of the tumor was determined by the presence of pleomorphism
, bizarre cells, and high numbers of mitotic figures.
The histological differential diagnosis to be considered is squamous cell carcinoma because of the cytological pleomorphism
The connective tissue stroma shows presence of areas of plump spindle shaped cells with mild nuclear and cellular pleomorphism
along with nuclear hyperchromatism.