The net result of the loss of collagen and its substitution by a degenerate elastotic substance in photodamaged skin
is to markedly alter the physical properties and mechanical function of this part of the skin.
Griffiths, "Interventions for photodamaged skin
," The Cochrane Database of Systematic Reviews, no.
looks old (Figure 6) and if one wants to avoid the aged and weather-beaten look there is no doubt that avoiding sun exposure is very helpful.
Dermatologists improve the appearance of photodamaged skin
via laser resurfacing.
A second set of 34 patients had only photodamaged skin
. This group included 27 women and 7 men, with an average age of 49.2 years.
As melatonin output decreases with age, (7) many people become more vulnerable to sleep disturbances that fail to adequately repair aging and photodamaged skin
The investigators concluded that photodamaged skin
may benefit from the use of novel topically applied products containing low-molecular-weight HS.
In the 1990s, an increasing weight of evidence emerged to show that topically applied retinoids improve the appearance of photodamaged skin
. At first, there was considerable resistance to the idea that one could significantly alter the degree of clinical photodamage with a few months of treatment with topical tretinoin.
(6.) Greenway HT and Pratt S, Skin tissue levels of carotenoids, vitamin A, and antioxidants in photodamaged skin
. La Jolla, CA: Mohs Surgery Unit, Division of Dermatology and Cutaneous Surgery, Scripps Clinic, 1999.
The topical 5-fluorouracil (5-FU) then treats the entire surrounding area of photodamaged skin
at risk for emergence of squamous cell carcinoma, including any residual subclinical AKs, he explained.
To test the age-reducing effects of topical application of 1.0% retinyl palmitate, scientists conducted a clinical study on 67 female volunteers with photodamaged skin
. Participants were randomly assigned to receive a topical formula containing retinyl palmitate (with vitamin E and moisturizers) or no treatment.