In a peer-reviewed letter to the editor of the Journal of Allergy and Clinical Immunology, which was published in July 2006, University of Florida pharmacists Leslie Hendeles and Randy Hatton warned that phenylephrine
is poorly absorbed into the bloodstream and therefore medications containing it will not work as well as those containing pseudoephedrine.
0 mN of tension) with submaximal concentrations of phenylephrine
Although serious morbidity associated with hypertension may be uncommon in the paediatric age group following systemic absorption of ocular phenylephrine
, pulmonary oedema and cardiac arrhythmias have been reported in an eight-year-old boy after an iatrogenic hypertensive crisis following 10% phenylephrine
As compared to the control group, incidence of hypotension was significantly less in phenylephrine
group as well as ephedrine group.
Acetylcholine chloride, L-NAME, indomethacin and Phenylephrine
chloride were purchased from Sigma (USA).
The syringe in group 1 (study group, n=45) contained ephedrine 10 mg plus phenylephrine
125 mcg that had reached 15 mL with normal saline serum (NaCl 0.
The Phase II, masked, non-randomized, cross-over study evaluated 12 subjects who underwent pupil dilation with topical phenylephrine
administered by a 32-[micro sign]L eye dropper (at one of two concentrations: 2.
Furthermore, recent evidence suggests that the direct application of fenproporex, a metabolic precursor to amphetamine, produces a vasorelaxant effect on phenylephrine
precontracted aortic rings (12).
In its advisory, the agency advised against using the fake versions of the following products: Mefanamic Acid (Dolfenal) 500 mg tablet; Dextromethorphan HBr + Phenylephrine
HCI + Paracetamol (Tuseran Forte) 15 mg / 10 mg / 325 mg Capsule; Loperamide (Diatabs) 2 mg Capsule; Ibuprofen + Paracetamol (Alaxan FR) 200 mg / 325 mg Capsule; and Phenylephrine
HCI / Chlorphenamine Maleate / Paracetamol (Neozep Forte) 10 mg / 2 mg / 500 mg Tablet.
In recent years there has been a move towards using phenylephrine
as the agent of choice in treating obstetric spinal hypotension.
for hypotension during spinal anesthesia for cesarean section: Multicenter, randomized, double blind controlled clinical trial *
To demonstrate this, we planned to evaluate the vessel in two aspects: the first part of the plan was to measure the capacity of endothelial nitric oxide synthase (eNOS) by using the immunohistochemistry method to understand the failure in the responses of the possible vasospasm and relaxation; the second part of the plan was to see and evaluate the responses of phenylephrine
and acetylcholine in the thoracic aorta in vitro given high fructose corn syrup (HFCS) and HFCS + CAPE.
Therefore, this study was designed to evaluate phenylephrine
4mg and 2mg intramuscular in comparison with ephedrine 45 mg intramuscular and saline, given 10 minutes before induction of spinal anaesthesia, in terms of hemodynamic stability, requirement for rescue IV vasopressors therapy and neonatal umbilical cord pH values.
Possible adverse effects from topical ocular 10% phenylephrine
were Amoxycillin capsules, Paracetamol Phenylephrine
HCl, Chlorpheniramine Maleate and Caffeine and Sinarest tablets.