GTI-2040 is also in a Phase II clinical trial
in the U.
In the Phase II clinical trial
for end stage colorectal cancer patients, 30% (6 of 20) were stabilized from 2 to 8 months and 1 patient experienced a partial tumor response, as determined by an independent lab.
Factors that may cause such a difference include the inability to show sufficient safety or activity in this phase II clinical trial
and the risk of adverse clinical results as SGN-40 moves into and advances in clinical trials.
The Phase II clinical trial
is a multicenter, double-blind, placebo-controlled study involving approximately 150 patients with diabetic peripheral neuropathy.
There are now two FDA approved products, one in Phase III clinical trials and two more in Phase II clinical trials
all using our delivery technologies.
Can-Fite is planning to commence preparations for phase II clinical trials
in patients with psoriasis, after the safety profile of the drug was demonstrated in couple of phase studies.
The Phase II clinical trial
is planned to be an international, multi-site clinical trial performed in the U.
The Company's lead drug, CF101, is being developed for the treatment of RA, and is currently in Phase II clinical trials
Having successfully divested non-oncology assets in 2005, the Company is now focused on the development of its core oncology product programs which include ProLindac(TM), an innovative polymer-platinum prodrug entering two Phase II clinical trials
, MuGard(TM), a supportive care treatment of mucositis for patients undergoing radiation therapy and chemotherapy for cancer, and other early stage oncology compounds that utilize the Company's unique drug delivery platforms.
CA4P is currently being investigated in a Phase II clinical trial
for the treatment of advanced and regional ATC and a Phase I/II trial in newly diagnosed ATC.
Seattle Genetics is conducting ongoing phase II clinical trials
of SGN-30 as a single agent in systemic ALCL and cutaneous ALCL.
CytRx is currently conducting a Phase II clinical trial
at ten centers across the U.
The Company believes that successfully demonstrating safety and efficacy in this latter Phase II clinical trial
could be sufficient to support product registration with the FDA.
Should the drug be well tolerated without further compromise to bone marrow function, and should there be hints of efficacy, we plan to move rapidly into a Phase II clinical trial
in an effort to demonstrate prolonged disease stabilization and survival.
NASDAQ: OXGN, XSSE: OXGN), a leading developer of biopharmaceutical compounds designed to treat cancer and certain ophthalmologic diseases, today announced that the Company has successfully completed patient enrollment in a Phase II clinical trial
for the treatment of imageable solid tumors.