The researchers conclude that 17[beta]-estradiol and other estrogens can downregulate phase II
enzyme activities in the uterus, thus potentially slowing the metabolism of reactive intermediates.
Dr Eugene Braunwald, chairman of the TIMI Study Group said: "We are very interested in learning in this Phase II
trial whether BB-10153 can successfully lyse clots and provide an acceptable safety profile in terms of bleeding risk.
In preparation for Phase II
, a proceeding will take place this fall to determine the backout credits.
However, the team found that only one of the compounds isolated from broccoli could stimulate the production of phase II
Proposed Phase II
The Phase II
proposal has been submitted to the DOE for their consideration of continued funding.
The results of the Phase I portion of the trial as well as the interim results from the ongoing Phase II
portion of the trial were further discussed during an oral presentation given this afternoon by Dr.
The SBIR/STTR Omnibus Solicitation describes statutory guidelines on levels of funding support and periods of project duration for SBIR and STTR Phase I and Phase II
Atlantis Phase II
is expected to include another i, 100 rooms in two towers with a connecting bridge, a 50,000 square-foot casino and themed entertainment/shopping arcade, 150,000 square feet of public space, five new restaurants and seven lounges, multi-level swimming pools, an extensive spa and sports center, and the dramatic expansion of the existing resort's waterscape, including a series of thrill waterslides that will be the first of their kind.
These findings will generate additional experimental programs during Phase II
for the final cupola model.
Biocon, India's largest Insulin producer has provided the source of insulin powder and Cardinal Health has manufactured the clinical supplies for this Phase II
study under contract with Bentley.
The assets of the National Land Fund's Phase II
are located primarily in the Southwest.
Biovitrum will provide financing for the Phase II
study at a amount of SEK 3 million.
As a result of these excellent findings, we are actively recruiting patients in two Phase II
studies that address first line therapies in colorectal and biliary cancers with DAVANAT([R])in combination with chemotherapeutics and biologics.
The multicenter, double blind, placebo-controlled Phase II
study involved 60 randomized patients with clinically significant PMS.
The Phase II
study will evaluate the efficacy of CB7630 administered daily to patients with chemotherapy-naE[macron]ve hormone refractory prostate cancer (HRPC) with a rising PSA (prostate specific antigen) despite hormonal therapy.