Neu-rological ailments such as hand tremors, peripheral neuritis
and headaches showed a prevalence of around 12% in the both the years.
Nitrofurantoin, the IDSA said at the time, "may become more useful as resistance to TMP-SMX increases," but was not considered first-line because of concerns about effectiveness (85% cure rate versus 90%-95% for other first-line agents) and safety, particularly regarding the rare but potentially serious occurrence of acute pulmonary reaction and the even rarer peripheral neuritis
90%-95% for other first-line agents) and safety, particularly regarding the rare but serious occurrence of acute pulmonary reaction and the even rarer peripheral neuritis
and Canadian authorities decided against boosting fortification to achieve the optimal levels needed for prevention of neural tube defects, because high levels of folic acid can mask pernicious anemia caused by vitamin B12 deficiency in the elderly, leading to irreversible neural damage, especially peripheral neuritis
Soon afterward, there were reports of peripheral neuritis
, a serious illness that eventually results in weakness of limbs and lack of coordination.