Main sites of metabolic modifications were (a) the terminal position of the pentyl
side chain, (b) the TMCP ring, and (c) the [alpha]-carbon atom next to the carbonyl function.
2,6-diethyl-1,3,5,7-tetramethyl substituted BODIPY derivatives with methyl, propyl, pentyl
and decyl substituents at the meso position have been reported (Nagi et al.
Fisher Esterification of Pentyl
Acetate Using a Dean Stark Trap.
AntiHSV-1 and anti-HIV-1 activity of gallic acid and pentyl
The polyethylene samples obtained with this Ni catalyst present large amounts of methyl, ethyl, propyl, butyl, pentyl
, and long branches with six or more carbons, as shown in Table 5.
The list of compounds synthesised by this fungus includes an extensive series of the acetic acid esters of straight-chained alkanes including those of pentyl
, hexyl, heptyl, octyl, sec-octyl and decyl alcohols.
In order to make the compounds more lipophilic, the carbon chain length of the parent DMSA was increased by controlled esterification with the corresponding alcohol (methyl, ethyl, propyl, isopropyl, butyl, isobutyl, pentyl
, isopentyl and hexyl; Fig.
Although both drugs are based on the transition state analog of sialic acid, zanamivir has a single substitution of a guanidinium group at the 4' position on the sugar ring, whereas oseltamivir has an amino group at the 4' position and, more importantly, a bulky hydrophobic pentyl
ether group replacing the glycerol side chain at the 6' position.