oxidative phosphorylation

The eletrochemical potential of this gradient is then harnessed in the synthesis of ATP by complex V (ATP synthase): this process is known as oxidative phosphorylation (Jennings and Ganote, 1976; Trump et al., 1976).

Mogrosides might affect mitochondrial glucose and fat metabolism, and change the process of oxidative phosphorylation, thus producing ROS.

Oxidative phosphorylation is the most efficient ATP producer.

PCP inhibits oxidative phosphorylation (3) and also induces morphologic alterations in the mitochondria (35).

Defects in oxidative phosphorylation are known to result in lactic acidemia, abnormal lactate: pyruvate ratios, accumulation of alanine, and increased acyl-carnitine levels in the plasma and urine [7].

(3) The consequence is the obstruction of the functional groups of respiratory enzymes and oxidative phosphorylation. Damage to these enzymes leads to a disturbance of cytochrome activity and consequently to a breakdown of the entire cellular function.

For example, oral administration of DEHP to rats induced liver mitochondrial swelling and reduced succinate dehydrogenase (SDH) activity (34), and studies with isolated rat liver mitochondria showed that MEHP caused uncoupling of oxidative phosphorylation and inhibition of SDH activity (35).

Defects in oxidative phosphorylation. Biochemical investigations in skeletal muscle and expression of the lesion in other cells.

The impairment of oxidative phosphorylation and induction of MPT are critical determinants for such mitochondrial dysfunction [106] and are dependent on GSK-3[beta] activity [107].

The fundamental bioenergetics of butterflies, bets, and bats involve coupling of respiration with oxidative phosphorylation and mitochondrial adenosine-5' triphosphate (ATP) generation.

Together they produce ATP by oxidative phosphorylation in an aerobic process.

The top 20 pathways with significant enrichment among DEGs are shown in Figure 4 (p<0.05), and mainly included amino acid metabolism, oxidative phosphorylation, lipid metabolism and pathways associated with certain diseases (e.g., Parkinson's disease and malaria).

Mitochondria are a double membrane organelle that is responsible for oxidative phosphorylation and ATP (Adenosine triphosphate) production and is found in cell cytoplasm.