hair cell

(redirected from Outer hair cell)
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  • noun

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a sensory epithelial cell present in the organ of Corti

References in periodicals archive ?
We evaluated the ototoxic effect of aminoglycosides on the outer hair cells of newborns in a neonatal intensive care unit (NICU) by means of distortion-product otoacoustic emissions (DPOAE) testing.
Because there is no commonly accepted gold standard of outer hair cell damage in humans, test accuracy can never be completely known for this method.
3) Therefore, if anything goes wrong in the cochlea, it is more apparent in the measures of the outer hair cells which is the origin of the otoacoustic emission and is an extremely sensitive measure of cochlear function.
It has been proposed that changes in hearing function among women may occur as a result of menses-associated variations in cochlear blood flow and/or changes in those outer hair cells that are sensitive to metabolic and hormonal fluctuations.
This leads to permanent damage to the outer hair cells of the cochlea, resulting in permanent hearing loss.
Previous research, however, has suggested the amplification depends on the outer hair cells in the cochlea changing their lengths in response to voltage changes.
153-158) Specifically, it has been shown that sulfhydryl compounds limit geatamicin-induced damage to outer hair cells in vitro and that in vivo gentamicin ototoxicity can be diminished with glutathione.
1] Since then, many investigations have shown that otoacoustic emissions are the result of the rapid contraction of the outer hair cells.
As outer hair cells become permanently damaged or nonfunctional, otoacoustic emissions provide greater accuracy and efficiency in predicting cochlear status than the audiogram.
This test checks the function of the tiny outer hair cells in the inner ear that are believed to be the most vulnerable to damage from prolonged noise exposure, and are crucial to normal hearing, the ability to hear soft (or low level sounds), and the ability to understand speech, especially in noisy environments.
Disabling the gene caused a loss of outer hair cells, a special sensory cell in the inner ear responsible for amplifying sound.
Scientists say they can now use the FGF20 gene profile to halt the loss of outer hair cells.
Mice lacking FGF20 were missing about two thirds of their outer hair cells.
OAEs entail a single probe inserted into the ear canal, measuring the active properties of the outer hair cells in the cochlea as low-level acoustic signals.
The ototoxicity, however, is permanent and is due to the death of the outer hair cells in the organ of Corti of the cochlea and type I sensory cells in the vestibular organ (MIM 580000).