In the present study, we included no information regarding exposure to organic arsenic
via the diet (fish, shellfish, rice, and wine); however, such exposure is less harmful.
V]), this helps to identify whether patients have increased excretion of relatively nontoxic organic arsenic
or increased excretion of toxic inorganic arsenic compounds; elevated speciated arsenic levels indicate toxic inorganic arsenic excretion and are more concerning.
Diet is a large source of both inorganic and organic arsenic
for typical individuals.
In 1944, the FDA approved the first arsenic-containing animal drug, 3-Nitro (also known as Roxarsone), whose active ingredient was organic arsenic
14 November 2011 - Ziopharm Oncology (NASDAQ:ZIOP) unveiled on Sunday results from preclinical trials of darinaparsin (Zinapar or ZIO-101), its new organic arsenic
, in prostate cancer.
Although most fish and seafood contain primarily (>90%) organic arsenic
, (23) up to 10% may be inorganic and bioavailable.
Drug development company ZIOPHARM Oncology Inc (Nasdaq:ZIOP) said on Monday that it has signed a licence and collaboration agreement to develop and commercialise its darinaparsin product (Zinapar or ZIO-101) and related organic arsenic
molecules in specified pan-Asian/Pacific territories.
Authorities probing the health hazards posed by poison gas agents left in Kamisu, Ibaraki Prefecture, by the Imperial Japanese Army have detected organic arsenic
compounds in rice harvested at four farms in the town, the prefectural government said Thursday.
Therefore, organic arsenic
is an approved ingredient in roxarsone, a feed additive used in poultry and swine.
Arsenobetaine (AB) is the major form of the organic arsenic
ubiquitously found in edible fish and shellfish at concentrations up to, and sometimes exceeding, 100 [micro]g/g, and usually accounting for virtually all of the arsenic present (3).
He tried every organic arsenic
compound he could obtain or synthesize, and the 606th was a compound now called arsphenamine.
Nasdaq: ZIOP), a drug development company employing small molecule and synthetic biology approaches to cancer therapy, announced today new preclinical data from two separate studies of darinaparsin (Zinapar([R]) or ZIO-101), a novel organic arsenic
, in various solid tumor models at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, taking place November 12-16 in San Francisco.
The multiple linear regression analyses performed with urinary arsenic were also repeated excluding those participants with significant organic arsenic
exposure, as estimated by the presence of detectable arsenocholine and arsenobetaine in their urine.
They found significant levels of inorganic arsenic, a carcinogen, in almost every product category, along with organic arsenic
, which is less toxic but still of concern.
The human body can metabolize organic arsenic
but not inorganic.