Plasma disposition curves for intramuscular and oral administration
of moxifloxacin were analyzed by use of the same procedure that was used for analysis of data determined for intravenous administration of the drug.
Conclusions and Clinical Relevance--Analysis of the results indicated that oral administration
of terbinafine at a dose of 60 mg/kg to Amazon parrots did not result in adverse effects and may be potentially of use in the treatment of aspergillosis.
Suppression of gonadotropins did not differ significantly by route of administration despite higher serum levels of levonorgestrel when taken orally "A direct effect on the endometrium nay enhance the clinical effectiveness of the vaginal route, making vaginal administration a potential alternative to oral administration
," he said.
Plasma concentrations after oral administration
of tramadol at a dose of 10 mg/kg were <40 ng/mL for the entire time period, but oral administration
at a dose of 30 mg/kg resulted in mean plasma concentrations > 100 ng/mL for approximately 6 hours after administration.
Repros supported its IND with animal model data that suggest vaginally administered doses of Proellex-V will result in greater anti-proliferative effects on tissues that respond to progesterone stimulation compared with oral administration
The experiment results indicated that an oral administration
of rice helps alleviate allergic symptoms, in particular, sneezing.
allergy company to initiate a Phase III trial for the oral administration
of liquid standardized allergenic extracts.
Objective We investigated the photoprotective effect of oral administration
of an extract of the natural antioxidant Polypodium leucotomos (PL).
Twenty-one healthy volunteers [either untreated or treated with oral psoralens (8-MOP or 5-MOP)] were enrolled in this study and exposed to solar radiation for evaluation of the following clinical parameters: immediate pigment darkening (IPD), minimal erythema dose (MED), minimal melanogenic dose (MMD), and minimal phototoxic dose (MPD) before and after topical or oral administration
This study follows the recent completion of a single dose Phase 1 study that demonstrated that the compound was well absorbed following oral administration
and was generally well tolerated.